QuickView for TWF1 (gene)

Gene Symbol:

TWF1 Homo sapiens

Full name:

twinfilin actin binding protein 1

Synonyms:

A6, PTK9, twinfilin-1, A6 protein tyrosine kinase, PTK9 protein tyrosine kinase 9, protein A6, protein tyrosine kinase 9, twinfilin, actin-binding protein, homolog 1

Genomic Location:

Chr 12: 42473793-42486445

Description:

This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1.

This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Saccharomyces cerevisiae ,  Schizosaccharomyces pombe ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GCATTTG_MIR105 ,  AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  TACTTGA_MIR26A_MIR26B ,  AML1_01 ,  OSF2_Q6 ,  ACATTCC_MIR1_MIR206 ,  CATTTCA_MIR203 ,  CAGCTTT_MIR320 ,  GTTTGTT_MIR495 ,  ATGCTGC_MIR103_MIR107 ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  ACTGAAA_MIR30A3P_MIR30E3P ,  RACCACAR_AML_Q6 ,  PTF1BETA_Q6 ,  AML1_Q6 ,  CCTGCTG_MIR214 ,  ACACTAC_MIR1423P

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miRNA binding sites
(Source: miRecords):

hsa-miR-1 Targeted Genes

Cytogenetic Map:

12q12

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