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QuickView for Tace;jsessionid=2B370222F07357542C739905C1140B15;jsessionid=215E770B277380A38858DF90654D6468 (gene)


Gene Symbol:
ADAM17 Bos taurus Bos taurus
Full name:
ADAM metallopeptidase domain 17
Synonyms:
N/A
Genomic Location:
Chr 11: 90693086-90737685
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
XM_595713
Protein Names
No proteins found.



GO Molecular Function

metallopeptidase activity | cation binding | metalloendopeptidase activity | protein-containing complex binding | signaling receptor binding | hydrolase activity | Notch binding | cytokine receptor binding | catalytic activity | protein domain specific binding | ion binding | integrin binding | cell adhesion molecule binding | protein binding | endopeptidase activity | PDZ domain binding | growth factor receptor binding | metal ion binding | peptidase activity | interleukin-6 receptor binding

GO Biological Process

positive regulation of cyclin-dependent protein serine/threonine kinase activity | regulation of leukocyte chemotaxis | metallopeptidase activity | membrane protein proteolysis | regulation of cell cycle process | positive regulation of locomotion | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | cell motility | response to lipopolysaccharide | proteolysis | regulation of localization | regulation of cell cycle G1/S phase transition | morphogenesis of an epithelium | positive regulation of peptidyl-tyrosine phosphorylation | defense response to other organism | regulation of immune system process | regulation of transforming growth factor beta receptor signaling pathway | negative regulation of cellular process | positive regulation of epithelial cell proliferation | positive regulation of signaling receptor activity | defense response | regulation of G1/S transition of mitotic cell cycle | positive regulation of phosphate metabolic process | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | cellular process | positive regulation of epidermal growth factor-activated receptor activity | regulation of cell motility | localization | metalloendopeptidase activity | negative regulation of signaling | positive regulation of protein kinase activity | regulation of response to cytokine stimulus | regulation of chemotaxis | response to hypoxia | positive regulation of tumor necrosis factor-mediated signaling pathway | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | tissue development | regulation of cellular process | positive regulation of cell growth | regulation of metabolic process | positive regulation of cyclin-dependent protein kinase activity | PMA-inducible membrane protein ectodomain proteolysis | epidermal growth factor receptor signaling pathway | positive regulation of cellular protein metabolic process | epithelium development | positive regulation of epithelial cell migration | response to stimulus | positive regulation of vascular endothelial cell proliferation | wound healing, spreading of cells | regulation of mitotic cell cycle phase transition | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | cell adhesion mediated by integrin | response to stress | membrane protein ectodomain proteolysis | positive regulation of T cell migration | regulation of cell proliferation | regulation of cell cycle phase transition | response to molecule of bacterial origin | positive regulation of blood vessel endothelial cell migration | ERBB signaling pathway | positive regulation of protein serine/threonine kinase activity | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | positive regulation of ERBB signaling pathway | epiboly | negative regulation of cellular response to transforming growth factor beta stimulus | locomotion | positive regulation of response to cytokine stimulus | regulation of protein tyrosine kinase activity | response to external biotic stimulus | regulation of cyclin-dependent protein serine/threonine kinase activity | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | cell migration | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | positive regulation of lymphocyte migration | wound healing | positive regulation of cell cycle | positive regulation of chemotaxis | response to lipid | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular response to high density lipoprotein particle stimulus | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | negative regulation of cellular response to growth factor stimulus | receptor transactivation | regulation of cellular component movement | morphogenesis of an epithelial sheet | regulation of endothelial cell migration | positive regulation of cell migration | regulation of cellular protein metabolic process | positive regulation of chemokine production | regulation of leukocyte migration | response to bacterium | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of leukocyte chemotaxis | regulation of T cell migration | regulation of tumor necrosis factor-mediated signaling pathway | regulation of protein metabolic process | positive regulation of signal transduction | defense response to bacterium | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of cytokine-mediated signaling pathway | regulation of locomotion | regulation of cellular response to growth factor stimulus | cellular response to lipoprotein particle stimulus | regulation of mitotic cell cycle | positive regulation of molecular function | regulation of signaling receptor activity | regulation of epidermal growth factor-activated receptor activity | protein metabolic process | negative regulation of transforming growth factor beta receptor signaling pathway | positive regulation of protein modification process | regulation of growth | response to organic substance | tissue morphogenesis | regulation of kinase activity | response to wounding | anatomical structure development | cell surface receptor signaling pathway | Notch receptor processing | metabolic process | cell adhesion | positive regulation of T cell chemotaxis | organic substance metabolic process | regulation of epidermal growth factor receptor signaling pathway | regulation of endothelial cell proliferation | positive regulation of leukocyte migration | positive regulation of kinase activity | regulation of phosphate metabolic process | positive regulation of cytokine production | positive regulation of endothelial cell migration | regulation of lymphocyte chemotaxis | regulation of epithelial cell migration | positive regulation of cytokine-mediated signaling pathway | defense response to Gram-positive bacterium | regulation of cell communication | regulation of blood vessel endothelial cell migration | negative regulation of signal transduction | signaling | positive regulation of growth | endopeptidase activity | regulation of ERBB signaling pathway | regulation of epithelial cell proliferation | positive regulation of phosphorylation | positive regulation of protein tyrosine kinase activity | cellular protein metabolic process | positive regulation of epidermal growth factor receptor signaling pathway | regulation of cytokine production | anatomical structure morphogenesis | response to biotic stimulus | developmental process | regulation of cell growth | regulation of chemokine production | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | cellular metabolic process | wound healing, spreading of epidermal cells | peptidase activity | positive regulation of cell motility | regulation of lymphocyte migration | regulation of cellular component organization | response to other organism | positive regulation of signaling | regulation of T cell chemotaxis | signal transduction | regulation of signaling | macromolecule metabolic process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | apical plasma membrane | ruffle | adherens junction | cell projection membrane | focal adhesion | cell | intrinsic component of membrane | ruffle membrane | cytoplasm | cell-substrate junction | intracellular organelle | actin cytoskeleton | membrane microdomain | leading edge membrane | apical part of cell | cell-cell junction | cell projection | plasma membrane | cell leading edge | membrane raft | integral component of plasma membrane | organelle | cell periphery | cell-substrate adherens junction | cytosol | cell surface | cytoskeleton | intracellular | cell junction | membrane | intrinsic component of plasma membrane