QuickView for Taci (gene)

Gene Symbol:

TNFRSF13B Homo sapiens

Full name:

TNF receptor superfamily member 13B

Synonyms:

CD267, CVID, CVID2, IGAD2, RYZN, TACI, TNFRSF14B, tumor necrosis factor receptor superfamily member 13B, transmembrane activator and CAML interactor, tumor necrosis factor receptor 13B

Genomic Location:

Chr 17: 16783123-16816127

Description:

The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF liga...

View Full Description

The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RYTTCCTG_ETS2_B ,  OCT1_Q6 ,  MGGAAGTG_GABP_B

Cytogenetic Map:

17p11.2

search → result