QuickView for Taok3 (gene)
- Gene Symbol:
- TAOK3
Homo sapiens - Full name:
- TAO kinase 3
- Synonyms:
- DPK, JIK, MAP3K18, hKFC-A, serine/threonine-protein kinase TAO3, CTCL-associated antigen HD-CL-09, JNK/SAPK-inhibitory kinase, STE20-like kinase, cutaneous T-cell lymphoma-associated antigen HD-CL-09, dendritic cell-derived protein kinase, jun kinase-inhibitory kinase, kinase from chicken homolog A, thousand and one amino acid protein 3
- Genomic Location:
- Chr 12: 117071989-117295133
- Description:
-
The protein encoded by this gene is a serine/threonine protein kinase that activates the p38/MAPK14 stress-activated MAPK cascade but inhibits the basal activity of the MAPK8/JNK cascade. The encoded protein is a member of the GCK subfamily of STE20-like kinases.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
12q24.23
GO Molecular Function
protein kinase regulator activity | kinase regulator activity | protein kinase inhibitor activity | ribonucleotide binding | nucleotide binding | enzyme inhibitor activity | carbohydrate derivative binding | protein serine/threonine kinase activity | molecular function regulator | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | MAP kinase kinase kinase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | kinase inhibitor activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
regulation of JUN kinase activity | negative regulation of JNK cascade | negative regulation of phosphorylation | regulation of cell cycle process | negative regulation of MAPK cascade | intracellular signal transduction | protein kinase regulator activity | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | negative regulation of protein phosphorylation | positive regulation of phosphate metabolic process | negative regulation of stress-activated protein kinase signaling cascade | cellular process | mitotic DNA integrity checkpoint | negative regulation of signaling | kinase regulator activity | protein kinase inhibitor activity | positive regulation of protein kinase activity | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | cellular aromatic compound metabolic process | regulation of G2/M transition of mitotic cell cycle | MAPK cascade | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | enzyme inhibitor activity | regulation of mitotic cell cycle phase transition | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | response to stress | negative regulation of G2/M transition of mitotic cell cycle | negative regulation of protein kinase activity | mitotic G2 DNA damage checkpoint | regulation of cell cycle phase transition | protein serine/threonine kinase activity | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | protein modification process | macromolecule modification | activation of protein kinase activity | molecular function regulator | stress-activated protein kinase signaling cascade | DNA repair | regulation of cellular response to stress | regulation of cell cycle G2/M phase transition | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of mitotic cell cycle phase transition | negative regulation of phosphate metabolic process | mitotic DNA damage checkpoint | negative regulation of catalytic activity | negative regulation of cell cycle G2/M phase transition | regulation of MAPK cascade | phosphorus metabolic process | cellular response to DNA damage stimulus | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | cellular response to stress | cell cycle | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | MAP kinase kinase kinase activity | protein autophosphorylation | regulation of nitrogen compound metabolic process | positive regulation of JNK cascade | positive regulation of intracellular signal transduction | regulation of cellular protein metabolic process | phosphorylation | negative regulation of stress-activated MAPK cascade | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | activation of MAPKK activity | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | regulation of mitotic cell cycle | positive regulation of molecular function | mitotic G2/M transition checkpoint | protein metabolic process | positive regulation of protein modification process | kinase inhibitor activity | regulation of kinase activity | DNA metabolic process | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | mitotic cell cycle | metabolic process | negative regulation of mitotic cell cycle | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | negative regulation of cellular protein metabolic process | positive regulation of kinase activity | regulation of phosphate metabolic process | regulation of JNK cascade | positive regulation of MAPK cascade | negative regulation of cell cycle | negative regulation of protein metabolic process | regulation of stress-activated MAPK cascade | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | positive regulation of MAP kinase activity | kinase activity | cellular protein modification process | heterocycle metabolic process | positive regulation of JUN kinase activity | positive regulation of metabolic process | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | DNA damage checkpoint | cell cycle checkpoint | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | intracellular | membrane
