Name: | tasosartan |
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PubChem Compound ID: | 60919 |
Molecular formula: | C23H21N7O |
Molecular weight: | 411.459 g/mol |
Synonyms: |
5,8-Dihydro-2,4-dimethyl-8-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)pyrido(2,3-d)pyrimidin-7(6H)-one; 145733-36-4; Pyrido(2,3-d)pyrimidin-7(6H)-one, 5,8-dihydro-2,4-dimethyl-8-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-; ANA-756; WAY-ANA-756; Verdia; Tasosartan; Tasosartan [USAN:INN]; WAY-126756
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Name: | tasosartan |
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Name (isomeric): | DB01349 |
Drug Type: | small molecule |
CAS number: | 145733-36-4 |
Indication: | Tasosartan is infrequently in the treatment of hypertension and heart failure. |
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Pharmacology: | By blocking the angiotensin II (AT1) receptor, the drug ultimately causes vasodilation, reduced secretion of vasopressin (ADH), reduced production and secretion of aldosterone, amongst other actions leading to the combined effect of a reduction of blood pressure. |
Mechanism of Action: |
Tasosartan is a selective, potent, orally active and long-acting nonpeptide Angiotensin II type 1 (AT1) receptor antagonist. Tasosartan blocks the renin-angiotensin-aldosterone system (RAAS) at the level of the AT1 receptor that mediates most, if not all, of the important actions of Ang II. Tasosartan binds reversibly to the AT1 receptors in vascu...
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Drug interaction: |
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