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QuickView for Tenoxicam (compound)
PubChem
| Name: | tenoxicam |
|---|---|
| PubChem Compound ID: | 5282194 |
| Molecular formula: | C13H11N3O4S2 |
| Molecular weight: | 337.376 g/mol |
| Synonyms: |
Mobiflex; Tenoxicam; Tilcotil (TN); D01767; Tilcotil; Ro-120068; Tenoxicam (JAN/USAN); 59804-37-4; Liman; Prestwick_849
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DrugBank
Identification
| Name: | tenoxicam |
|---|---|
| Name (isomeric): | DB00469 |
| Drug Type: | small molecule |
| Synonyms: |
Tenoxicamum [INN-Latin]
|
| Brand: | Tilcotil, Apo-Tenoxicam, Novo-Tenoxicam |
| Category: | Cyclooxygenase Inhibitors |
| CAS number: | 59804-37-4 |
Pharmacology
| Indication: | For the treatment of rheumatoid arthritis, osteoarthritis, backache, and pain. |
|---|---|
| Pharmacology: | Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain. |
| Mechanism of Action: |
The antiinflammatory effects of tenoxicam may result from the inhibition of the enzyme cycooxygenase and the subsequent peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, their inhibition accounts for the peripheral analgesic effects of tenoxicam. Antipyresis may occur by central action on the hypothalamus...
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| Absorption: | Oral absorption of tenoxicam is rapid and complete (absolute bioavailability 100%). |
| Protein binding: | 99% |
| Biotransformation: | Tenoxicam is metabolized in the liver to several pharmacologically inactive metabolites (mainly 5'-hydroxy-tenoxicam). |
| Half Life: | 72 hours (range 59 to 74 hours) |
| Affected organisms: | Humans and other mammals |
Interactions
| Drug interaction: |
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Targets
Enzymes
Transporters
