QuickView for Tf (gene)

Gene Symbol:

TF Homo sapiens

Full name:

transferrin

Synonyms:

HEL-S-71p, PRO1557, PRO2086, TFQTL1, serotransferrin, beta-1 metal-binding globulin, epididymis secretory sperm binding protein Li 71p, siderophilin

Genomic Location:

Chr 3: 134947925-134980325

Description:

This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticul...

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This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA1_01 ,  GATA3_01 ,  CTTTGA_LEF1_Q2 ,  TGACCTY_ERR1_Q2 ,  TGTTTGY_HNF3_Q6 ,  CTTTGT_LEF1_Q2

Cytogenetic Map:

3q22.1

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