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QuickView for Tgfb1i1 (gene)


Gene Symbol:
TGFB1I1 Homo sapiens Homo sapiens
Full name:
transforming growth factor beta 1 induced transcript 1
Synonyms:
ARA55, HIC-5, HIC5, TSC-5, transforming growth factor beta-1-induced transcript 1 protein, androgen receptor coactivator 55 kDa protein, androgen receptor coactivator ARA55, androgen receptor-associated protein of 55 kDa, hydrogen peroxide-inducible clone 5 protein, hydrogen peroxide-inducible clone-5
Genomic Location:
Chr 16: 31390985-31396781
Description:
This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isof...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 16
16p11.2





GO Molecular Function

cation binding | hormone receptor binding | signaling receptor binding | androgen receptor binding | nuclear hormone receptor binding | ion binding | transcription coactivator activity | I-SMAD binding | protein binding | transcription factor binding | steroid hormone receptor binding | transcription coregulator activity | SMAD binding | metal ion binding | Roundabout binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | proteolysis | morphogenesis of an epithelium | response to hormone | regulation of transforming growth factor beta receptor signaling pathway | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | negative regulation of fat cell differentiation | androgen receptor signaling pathway | hormone-mediated signaling pathway | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | negative regulation of signaling | positive regulation of epithelial to mesenchymal transition | positive regulation of nitrogen compound metabolic process | tissue development | regulation of fat cell differentiation | regulation of cell differentiation | regulation of cellular process | cellular response to lipid | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | response to stimulus | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | cellular protein catabolic process | response to temperature stimulus | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | positive regulation of RNA biosynthetic process | steroid hormone mediated signaling pathway | cellular biosynthetic process | embryo development | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of nucleic acid-templated transcription | negative regulation of cellular response to transforming growth factor beta stimulus | cellular response to hormone stimulus | nitrogen compound metabolic process | regulation of signal transduction | Wnt signaling pathway | multicellular organism development | regulation of gene expression | response to lipid | protein catabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | negative regulation of cellular response to growth factor stimulus | positive regulation of cell differentiation | biosynthetic process | aromatic compound biosynthetic process | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | positive regulation of signal transduction | transcription coactivator activity | regulation of RNA metabolic process | regulation of cellular response to growth factor stimulus | embryonic morphogenesis | ubiquitin-dependent SMAD protein catabolic process | protein metabolic process | negative regulation of transforming growth factor beta receptor signaling pathway | response to organic substance | tissue morphogenesis | cellular macromolecule catabolic process | anatomical structure development | cell surface receptor signaling pathway | metabolic process | cell fate commitment | regulation of RNA biosynthetic process | cell adhesion | morphogenesis of embryonic epithelium | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | response to heat | cellular response to steroid hormone stimulus | transcription, DNA-templated | intracellular receptor signaling pathway | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | positive regulation of transforming growth factor beta receptor signaling pathway | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular protein metabolic process | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of developmental process | developmental process | intracellular steroid hormone receptor signaling pathway | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | epithelial cell differentiation | regulation of epithelial to mesenchymal transition | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | response to steroid hormone | modification-dependent protein catabolic process | negative regulation of cell differentiation | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | extracellular matrix | adherens junction | focal adhesion | cell | nuclear lumen | cytoplasm | collagen-containing extracellular matrix | cell-substrate junction | intracellular organelle | extracellular region | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cell-substrate adherens junction | nuclear matrix | cytoskeleton | intracellular | cell junction | nuclear periphery