QuickView for Thbs2 (gene)

Gene Symbol:

THBS2 Homo sapiens

Full name:

thrombospondin 2

Synonyms:

TSP2, thrombospondin-2

Genomic Location:

Chr 6: 169357800-169396062

Description:

The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate ...

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The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  RYTTCCTG_ETS2_B ,  RSRFC4_01 ,  SMAD3_Q6 ,  AAANWWTGC_UNKNOWN ,  RSRFC4_Q2 ,  STAT6_01 ,  CTAWWWATA_RSRFC4_Q2 ,  TATAAA_TATA_01 ,  TST1_01 ,  GTTTGTT_MIR495 ,  STAT5A_03 ,  POU1F1_Q6 ,  TTGCCAA_MIR182 ,  MEF2_03 ,  TBP_01 ,  EVI1_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-495

Cytogenetic Map:

6q27

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