QuickView for Thra1 (gene)

Gene Symbol:

Thra Mus musculus

Full name:

thyroid hormone receptor alpha

Synonyms:

6430529J03Rik, AW259572, Erba, Nr1a1, Rvr, T3R[a], T3Ralpha, Thra1, Thra2, c-erbA-1, c-erbA-alpha, c-erbAalpha, thyroid hormone receptor alpha, TR alpha 1, TR alpha 2, nuclear receptor subfamily 1 group A member 1

Genomic Location:

Chr 11: 98603187-98626425

Description:

The protein encoded by this gene is one of several nuclear hormone receptors that bind thyroid hormones such as triiodothyronine and thyroxine with high affinity. The encoded protein is a transcription factor that can activate or repress transcription. Several alternatively spliced transcript variants of this gene have been described, but the full-...

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The protein encoded by this gene is one of several nuclear hormone receptors that bind thyroid hormones such as triiodothyronine and thyroxine with high affinity. The encoded protein is a transcription factor that can activate or repress transcription. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E47_01 ,  E47_02 ,  CDPCR1_01 ,  CEBPA_01 ,  CEBPB_02 ,  PBX1_02 ,  OCT1_01 ,  OCT1_02 ,  OCT1_04 ,  PAX5_01 ,  OCT1_05 ,  CREBP1_Q2 ,  CEBP_Q2 ,  OCT1_Q6 ,  SP1_Q6 ,  HNF1_C ,  OCT_C ,  EGR2_01 ,  FREAC2_01 ,  FREAC3_01 ,  WHN_B ,  ZF5_B ,  OCT1_B ,  AREB6_01 ,  AREB6_03 ,  MEIS1_01 ,  CHX10_01 ,  VDR_Q3 ,  ZIC3_01 ,  NKX3A_01 ,  AP2ALPHA_01 ,  FOXO4_01 ,  FOXO1_01 ,  FOXO1_02 ,  FOXO4_02 ,  NCX_01 ,  NKX22_01 ,  ERR1_Q2 ,  CEBPDELTA_Q6 ,  EFC_Q6 ,  GCM_Q2 ,  HNF6_Q6 ,  HOXA4_Q2 ,  PTF1BETA_Q6 ,  ATF1_Q6 ,  TFIII_Q6 ,  SF1_Q6 ,  SMAD4_Q6 ,  CEBP_Q3 ,  STAT_Q6 ,  OCT_Q6 ,  PIT1_Q6 ,  CEBP_Q2_01 ,  OCT1_Q5_01 ,  SP1_Q2_01 ,  T3R_Q6 ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  GGGNRMNNYCAT_UNKNOWN ,  GGGYGTGNY_UNKNOWN ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  CACTTTG_MIR520G_MIR520H ,  GTGGGTGK_UNKNOWN ,  GACAGGG_MIR339 ,  TCTCTCC_MIR185 ,  GAGCTGG_MIR337 ,  GTGCAAA_MIR507 ,  GGGATGC_MIR3245P ,  TGCGCANK_UNKNOWN ,  YGTCCTTGR_UNKNOWN ,  TAATTA_CHX10_01 ,  CAGGTG_E12_Q6 ,  GTGACGY_E4F1_Q6 ,  TTGTTT_FOXO4_01 ,  RTAAACA_FREAC2_01 ,  TGTTTGY_HNF3_Q6 ,  GGGAGGRR_MAZ_Q6 ,  YATGNWAAT_OCT_C ,  CCCNNGGGAR_OLF1_01 ,  GGGTGGRR_PAX4_03 ,  GGGCGGR_SP1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-185 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-339 ,  Predicted Gene Targets for miR-363 ,  Predicted Gene Targets for miR-500

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