QuickView for Thsd7a (gene)

Gene Symbol:

THSD7A Homo sapiens

Full name:

thrombospondin type 1 domain containing 7A

Synonyms:

thrombospondin type-1 domain-containing protein 7A, thrombospondin, type I, domain containing 7A

Genomic Location:

Chr 7: 11380695-11838349

Description:

The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be ass...

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The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Gallus gallus ,  Pan troglodytes ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

7p21.3

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