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QuickView for Thy-1;jsessionid=011CF923678866240A0AFA39DB3FF7BC;jsessionid=469EB5DB5BA323E16AE04AF9D11394C5 (gene)


Gene Symbol:
THY1 Homo sapiens Homo sapiens
Full name:
Thy-1 cell surface antigen
Synonyms:
CD90, CDw90, thy-1 membrane glycoprotein, Thy-1 T-cell antigen, thy-1 antigen
Genomic Location:
Chr 11: 118794098-118799064
Description:
This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene ma...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 11
11q23.3


Transcripts Names
NM_006288
NM_001311160
NM_001311162
Protein Names
P04216
Q16008
Q9NSP1
B0YJA4



GO Molecular Function

kinase binding | enzyme activator activity | GTPase activator activity | protein kinase binding | enzyme binding | protein-containing complex binding | lipid binding | signaling receptor binding | GTPase regulator activity | carbohydrate derivative binding | phospholipid binding | molecular function regulator | anion binding | glycolipid binding | ion binding | integrin binding | cell adhesion molecule binding | protein binding | phosphatidylinositol binding | GPI anchor binding | enzyme regulator activity

GO Biological Process

positive regulation of immune response | positive regulation of release of sequestered calcium ion into cytosol | negative regulation of phosphorylation | positive regulation of locomotion | negative regulation of immune system process | positive regulation of cellular component organization | regulation of cell morphogenesis | regulation of neurogenesis | immune response-regulating signaling pathway | positive regulation of adherens junction organization | regulation of cellular localization | enzyme activator activity | regulation of cell development | regulation of localization | cell-substrate adhesion | eye development | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | negative regulation of cellular process | negative regulation of kinase activity | integrin-mediated signaling pathway | positive regulation of lymphocyte activation | cell differentiation | immune response-activating cell surface receptor signaling pathway | T cell receptor signaling pathway | adherens junction assembly | nervous system development | negative regulation of protein phosphorylation | cellular chemical homeostasis | neurogenesis | positive regulation of cell adhesion | positive regulation of cellular component movement | generation of neurons | blood vessel morphogenesis | positive regulation of GTPase activity | focal adhesion assembly | neural retina development | cellular process | negative regulation of axonogenesis | regulation of cell motility | localization | cellular homeostasis | negative regulation of signaling | neuron development | cell-substrate adherens junction assembly | negative regulation of T cell receptor signaling pathway | positive regulation of heterotypic cell-cell adhesion | GTPase activator activity | macromolecule localization | positive regulation of catalytic activity | negative regulation of cell migration | regulation of neuron projection development | negative regulation of cellular metabolic process | regulation of T cell receptor signaling pathway | regulation of cell differentiation | cell junction assembly | negative regulation of cell motility | regulation of immune response | regulation of cellular process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | regulation of cellular extravasation | cellular component organization | negative regulation of cell morphogenesis involved in differentiation | calcium ion homeostasis | retinal cone cell differentiation | response to stimulus | vasculature development | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | GTPase regulator activity | positive regulation of cation transmembrane transport | regulation of heterotypic cell-cell adhesion | negative regulation of protein kinase activity | negative regulation of neuron projection development | tube morphogenesis | positive regulation of cell-cell adhesion | receptor clustering | positive regulation of cell activation | cellular localization | cardiovascular system development | regulation of neuron projection regeneration | positive regulation of T cell activation | immune response-activating signal transduction | negative regulation of metabolic process | cellular component assembly | protein modification process | regulation of cell adhesion | macromolecule modification | cell-cell signaling | positive regulation of cell-matrix adhesion | molecular function regulator | eye photoreceptor cell differentiation | metal ion homeostasis | blood vessel development | regulation of cellular response to stress | regulation of calcium ion transport into cytosol | regulation of protein tyrosine kinase activity | positive regulation of cell junction assembly | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | positive regulation of calcium ion transmembrane transport | regulation of adherens junction organization | adherens junction organization | multicellular organism development | negative regulation of catalytic activity | phosphorus metabolic process | regulation of axonogenesis | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | retina morphogenesis in camera-type eye | localization within membrane | regulation of T cell activation | regulation of neuron differentiation | protein localization to membrane | regulation of lymphocyte activation | retinal cone cell development | cellular ion homeostasis | animal organ morphogenesis | positive regulation of ion transmembrane transport | positive regulation of cytosolic calcium ion concentration | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cell-substrate adhesion | cell-substrate junction assembly | regulation of cellular component movement | positive regulation of hydrolase activity | regulation of release of sequestered calcium ion into cytosol | positive regulation of cell migration | regulation of cellular protein metabolic process | angiogenesis | phosphorylation | regulation of calcium ion transmembrane transport | regulation of GTPase activity | protein phosphorylation | cation homeostasis | regulation of leukocyte migration | phosphate-containing compound metabolic process | sensory organ development | positive regulation of cellular extravasation | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | eye morphogenesis | regulation of protein metabolic process | cellular calcium ion homeostasis | homeostatic process | regulation of protein phosphorylation | regulation of locomotion | positive regulation of transport | eye photoreceptor cell development | positive regulation of molecular function | neuron differentiation | regulation of Rho-dependent protein serine/threonine kinase activity | activation of immune response | regulation of cell morphogenesis involved in differentiation | protein metabolic process | positive regulation of focal adhesion assembly | negative regulation of cell projection organization | retina development in camera-type eye | regulation of kinase activity | regulation of focal adhesion assembly | anatomical structure development | cell surface receptor signaling pathway | metabolic process | positive regulation of leukocyte activation | cellular protein localization | chemical homeostasis | cell adhesion | positive regulation of cellular component biogenesis | organic substance metabolic process | regulation of sequestering of calcium ion | animal organ development | positive regulation of ion transport | negative regulation of neuron differentiation | positive regulation of cell-substrate adhesion | negative regulation of cellular protein metabolic process | regulation of cell activation | negative regulation of cellular component movement | positive regulation of leukocyte migration | ion homeostasis | regulation of phosphate metabolic process | cytoskeleton organization | regulation of ion transmembrane transport | antigen receptor-mediated signaling pathway | cell-cell adhesion | camera-type eye development | anatomical structure formation involved in morphogenesis | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | cell-matrix adhesion | cell development | negative regulation of peptidyl-tyrosine phosphorylation | protein localization | cellular protein metabolic process | enzyme regulator activity | anatomical structure morphogenesis | cellular macromolecule localization | camera-type eye morphogenesis | positive regulation of calcium ion transport into cytosol | regulation of nervous system development | regulation of developmental process | regulation of ion transport | negative regulation of neuron projection regeneration | developmental process | organelle organization | regulation of calcium ion transport | cellular protein modification process | tube development | regulation of cell junction assembly | regulation of transport | regulation of cell-cell adhesion | photoreceptor cell development | cellular metal ion homeostasis | regulation of cell projection organization | immune system process | cellular metabolic process | photoreceptor cell differentiation | positive regulation of cell motility | negative regulation of protein tyrosine kinase activity | negative regulation of cell development | circulatory system development | divalent inorganic cation homeostasis | negative regulation of locomotion | positive regulation of leukocyte cell-cell adhesion | camera-type eye photoreceptor cell differentiation | negative regulation of cell differentiation | regulation of cellular component organization | positive regulation of calcium ion transport | signal transduction | regulation of signaling | regulation of cell-matrix adhesion | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | dendrite | intracellular membrane-bounded organelle | apical plasma membrane | neuron projection | intrinsic component of external side of plasma membrane | axolemma | somatodendritic compartment | adherens junction | cell projection membrane | focal adhesion | cell body | cell | neuronal cell body | distal axon | intrinsic component of membrane | external side of plasma membrane | cytoplasm | cell-substrate junction | intracellular organelle | endoplasmic reticulum | membrane microdomain | dendritic tree | anchored component of plasma membrane | leading edge membrane | main axon | apical part of cell | cell projection | endomembrane system | plasma membrane | cell leading edge | membrane raft | vesicle | neuronal cell body membrane | extracellular exosome | site of polarized growth | anchored component of membrane | integral component of plasma membrane | extracellular region | dendrite membrane | membrane-bounded organelle | extracellular vesicle | organelle | anchored component of external side of plasma membrane | extracellular space | cell periphery | cell body membrane | axon | cell-substrate adherens junction | growth cone | cytosol | cell surface | intracellular | cell junction | myelin sheath | membrane | neuron projection membrane | intrinsic component of plasma membrane