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QuickView for Timm50 (gene)


Gene Symbol:
TIMM50 Homo sapiens Homo sapiens
Full name:
translocase of inner mitochondrial membrane 50
Synonyms:
MGCA9, TIM50, TIM50L, mitochondrial import inner membrane translocase subunit TIM50, Tim50-like protein, homolog of yeast Tim50
Genomic Location:
Chr 19: 44662892-44673368
Description:
This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal, or presequence, on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the m...
Orthologs:
Mus musculus Rattus norvegicus C. elegans Saccharomyces cerevisiae Schizosaccharomyces pombe Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 19
19q13.2





GO Molecular Function

protein serine/threonine phosphatase activity | nucleic acid binding | protein-containing complex binding | phosphatase activity | signaling receptor binding | hydrolase activity | cytokine receptor binding | protein tyrosine phosphatase activity | catalytic activity | ribonucleoprotein complex binding | phosphoprotein phosphatase activity | hydrolase activity, acting on ester bonds | organic cyclic compound binding | protein binding | phosphoric ester hydrolase activity | growth factor receptor binding | interleukin-2 receptor binding | heterocyclic compound binding | RNA binding

GO Biological Process

protein serine/threonine phosphatase activity | protein dephosphorylation | release of cytochrome c from mitochondria | protein localization to mitochondrion | establishment of localization | membrane organization | intracellular transport | cellular process | localization | protein transport | protein transmembrane import into intracellular organelle | establishment of protein localization to mitochondrion | macromolecule localization | protein import into mitochondrial matrix | establishment of localization in cell | regulation of cellular process | cellular component organization | phosphatase activity | response to stimulus | intracellular protein transport | programmed cell death | cellular localization | apoptotic mitochondrial changes | protein modification process | mitochondrion organization | macromolecule modification | protein tyrosine phosphatase activity | apoptotic process | nitrogen compound metabolic process | phosphorus metabolic process | organic substance transport | mitochondrial transport | phosphoprotein phosphatase activity | peptide transport | protein localization to organelle | phosphate-containing compound metabolic process | protein import | mitochondrial membrane organization | cell communication | apoptotic signaling pathway | protein metabolic process | establishment of protein localization to organelle | metabolic process | cellular protein localization | amide transport | mitochondrial transmembrane transport | organic substance metabolic process | cell death | establishment of protein localization | dephosphorylation | transmembrane transport | signaling | intracellular protein transmembrane transport | protein localization | cellular protein metabolic process | cellular macromolecule localization | protein targeting to mitochondrion | organelle organization | cellular protein modification process | peptidyl-tyrosine dephosphorylation | protein transmembrane transport | protein targeting | cellular metabolic process | signal transduction | macromolecule metabolic process

GO Cellular Component

integral component of membrane | organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | organelle membrane | cell | nuclear lumen | intrinsic component of membrane | cytoplasm | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | nuclear speck | mitochondrion | membrane-bounded organelle | nucleus | organelle | mitochondrial envelope | membrane-enclosed lumen | mitochondrial inner membrane presequence translocase complex | mitochondrial membrane | intracellular | membrane