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QuickView for Tip49a (gene)


Gene Symbol:
RUVBL1 Homo sapiens Homo sapiens
Full name:
RuvB like AAA ATPase 1
Synonyms:
ECP-54, ECP54, INO80H, NMP 238, NMP238, PONTIN, Pontin52, RVB1, TIH1, TIP49, TIP49A, ruvB-like 1, 49 kDa TATA box-binding protein-interacting protein, 49 kDa TBP-interacting protein, 54 kDa erythrocyte cytosolic protein, INO80 complex subunit H, RuvB (E coli homolog)-like 1, RuvB-like AAA ATPase, TAP54-alpha, TATA binding protein interacting protein 49 kDa, TIP60-associated protein 54-alpha, nuclear matrix protein 238, pontin 52
Genomic Location:
Chr 3: 129282493-129325332
Description:
This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone m...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3q21.3





GO Molecular Function

ADP binding | cadherin binding | enzyme binding | ribonucleotide binding | ATP-dependent DNA helicase activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP-dependent 5'-3' DNA helicase activity | ATP binding | TFIID-class transcription factor binding | anion binding | ATPase binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | ATP-dependent helicase activity | ion binding | organic cyclic compound binding | cell adhesion molecule binding | transcription coactivator activity | purine ribonucleoside triphosphate binding | DNA helicase activity | protein binding | transcription factor binding | TBP-class protein binding | RNA polymerase II transcription factor binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | DNA-dependent ATPase activity | helicase activity | drug binding | transcription coregulator activity | basal RNA polymerase II transcription machinery binding | heterocyclic compound binding | 5'-3' DNA helicase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

protein modification by small protein removal | RNA metabolic process | positive regulation of macromolecule biosynthetic process | proteolysis | regulation of localization | nucleosome organization | peptidyl-amino acid modification | histone modification | male gamete generation | positive regulation of cellular biosynthetic process | cellular process | box C/D snoRNP assembly | chromatin organization | CENP-A containing chromatin organization | multicellular organismal reproductive process | regulation of telomerase RNA localization to Cajal body | positive regulation of nitrogen compound metabolic process | regulation of canonical Wnt signaling pathway | gamete generation | DNA geometric change | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | protein deubiquitination | ATP-dependent DNA helicase activity | histone H4 acetylation | CENP-A containing nucleosome assembly | response to stimulus | response to stress | cellular nitrogen compound biosynthetic process | beta-catenin-TCF complex assembly | protein-DNA complex assembly | reproduction | peptidyl-lysine acetylation | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | protein modification process | cellular biosynthetic process | DNA recombination | macromolecule modification | DNA repair | regulation of nucleic acid-templated transcription | ATP-dependent 5'-3' DNA helicase activity | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | protein acetylation | cellular response to DNA damage stimulus | ATP-dependent chromatin remodeling | regulation of gene expression | centromere complex assembly | cellular response to stress | cell cycle | positive regulation of cellular metabolic process | DNA replication-independent nucleosome assembly | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | histone acetylation | internal peptidyl-lysine acetylation | biosynthetic process | cell division | histone H2A acetylation | aromatic compound biosynthetic process | cellular protein-containing complex assembly | DNA duplex unwinding | regulation of cellular metabolic process | chromatin remodeling | positive regulation of signal transduction | transcription coactivator activity | regulation of RNA metabolic process | DNA helicase activity | multicellular organism reproduction | protein-containing complex assembly | protein metabolic process | regulation of growth | positive regulation of telomerase RNA localization to Cajal body | DNA metabolic process | chromatin assembly or disassembly | metabolic process | regulation of RNA biosynthetic process | peptidyl-lysine modification | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | ribonucleoprotein complex assembly | protein modification by small protein conjugation or removal | regulation of Wnt signaling pathway | DNA packaging | transcription, DNA-templated | chromatin assembly | positive regulation of canonical Wnt signaling pathway | regulation of cell communication | covalent chromatin modification | regulation of transcription, DNA-templated | histone exchange | internal protein amino acid acetylation | cellular protein metabolic process | cellular macromolecule biosynthetic process | organelle organization | DNA replication-independent nucleosome organization | spermatogenesis | cellular protein modification process | positive regulation of nucleic acid-templated transcription | DNA conformation change | transcription coregulator activity | heterocycle metabolic process | nucleosome assembly | positive regulation of metabolic process | chromosome organization | ribonucleoprotein complex biogenesis | chromatin remodeling at centromere | positive regulation of Wnt signaling pathway | cellular metabolic process | 5'-3' DNA helicase activity | sexual reproduction | positive regulation of signaling | regulation of signaling | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

R2TP complex | chromosome | intracellular membrane-bounded organelle | catalytic complex | microtubule organizing center | cell | nuclear lumen | MLL1/2 complex | histone acetyltransferase complex | cytoplasm | H4/H2A histone acetyltransferase complex | intracellular organelle | MLL1 complex | histone methyltransferase complex | Swr1 complex | protein-containing complex | methyltransferase complex | nucleoplasm | chromatin | nuclear chromosome | ribonucleoprotein complex | vesicle | transferase complex | extracellular exosome | microtubule cytoskeleton | Ino80 complex | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | SWI/SNF superfamily-type complex | extracellular space | membrane-enclosed lumen | protein acetyltransferase complex | nuclear matrix | nuclear chromatin | ATPase complex | cytosol | cytoskeleton | intracellular | membrane | NuA4 histone acetyltransferase complex | nuclear periphery