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QuickView for Tis11d (gene)


Gene Symbol:
ZFP36L2 Homo sapiens Homo sapiens
Full name:
ZFP36 ring finger protein like 2
Synonyms:
BRF2, ERF-2, ERF2, RNF162C, TIS11D, mRNA decay activator protein ZFP36L2, EGF-response factor 2, TPA-induced sequence 11d, ZFP36-like 2, butyrate response factor 2, zinc finger protein 36, C3H type-like 1, zinc finger protein 36, C3H type-like 2, zinc finger protein 36, C3H1 type-like 2, zinc finger protein, C3H type, 36-like 2
Genomic Location:
Chr 2: 43304210-43307249
Description:
This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 2
2p21


Transcripts Names
NM_006887
Protein Names
P47974
Q9BSJ3
Q53TB4



GO Molecular Function

RNA polymerase II transcription factor activity, sequence-specific DNA binding | cation binding | nucleic acid binding | mRNA binding | DNA binding | ion binding | AU-rich element binding | organic cyclic compound binding | protein binding | DNA-binding transcription factor activity | mRNA 3'-UTR AU-rich region binding | mRNA 3'-UTR binding | metal ion binding | heterocyclic compound binding | RNA binding

GO Biological Process

RNA metabolic process | regulation of cell cycle process | response to cytokine | regulation of B cell activation | intracellular signal transduction | somatic stem cell population maintenance | regulation of immune system process | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cellular response to tumor necrosis factor | cell differentiation | negative regulation of fat cell differentiation | cellular process | organic substance catabolic process | cellular response to granulocyte macrophage colony-stimulating factor stimulus | lymphocyte differentiation | immune system development | stem cell population maintenance | regulation of cell cycle | response to growth factor | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of fat cell differentiation | regulation of cell differentiation | positive regulation of mRNA catabolic process | regulation of mRNA stability | regulation of cellular process | leukocyte activation | cellular response to lipid | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | MAPK cascade | mRNA catabolic process | response to transforming growth factor beta | T cell activation | response to stimulus | regulation of mitotic cell cycle phase transition | cellular response to fibroblast growth factor stimulus | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | signal transduction by protein phosphorylation | response to stress | posttranscriptional regulation of gene expression | regulation of cell cycle phase transition | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | negative regulation of metabolic process | hemopoiesis | protein modification process | mRNA metabolic process | nuclear-transcribed mRNA catabolic process | macromolecule modification | nucleobase-containing compound catabolic process | regulation of lymphocyte differentiation | regulation of nucleic acid-templated transcription | somatic stem cell division | leukocyte differentiation | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | negative regulation of mitotic cell cycle phase transition | 3'-UTR-mediated mRNA destabilization | multicellular organism development | phosphorus metabolic process | response to granulocyte macrophage colony-stimulating factor | regulation of gene expression | response to lipid | RNA catabolic process | stem cell division | positive regulation of cellular metabolic process | regulation of lymphocyte activation | regulation of nitrogen compound metabolic process | definitive hemopoiesis | regulation of RNA stability | response to corticosteroid | regulation of transcription by RNA polymerase II | cellular response to cytokine stimulus | cell proliferation | cell division | regulation of cellular protein metabolic process | cellular response to glucocorticoid stimulus | phosphorylation | protein phosphorylation | cellular response to corticosteroid stimulus | phosphate-containing compound metabolic process | mRNA destabilization | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | aromatic compound catabolic process | regulation of RNA metabolic process | regulation of stem cell differentiation | regulation of mitotic cell cycle | lymphocyte activation | cellular response to transforming growth factor beta stimulus | cellular response to epidermal growth factor stimulus | T cell differentiation | protein metabolic process | DNA-binding transcription factor activity | response to organic substance | T cell differentiation in thymus | regulation of hemopoiesis | response to wounding | cellular macromolecule catabolic process | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | negative regulation of mitotic cell cycle | nucleobase-containing compound metabolic process | organic substance metabolic process | regulation of B cell differentiation | maintenance of cell number | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | regulation of mRNA catabolic process | negative regulation of cellular protein metabolic process | regulation of cell activation | negative regulation of stem cell differentiation | RNA destabilization | cellular response to steroid hormone stimulus | negative regulation of translation | cell activation | response to epidermal growth factor | negative regulation of cell cycle | negative regulation of protein metabolic process | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular protein metabolic process | regulation of developmental process | developmental process | cellular protein modification process | response to fibroblast growth factor | ERK1 and ERK2 cascade | heterocycle metabolic process | positive regulation of metabolic process | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | negative regulation of cell cycle process | response to tumor necrosis factor | cellular response to organic substance | response to steroid hormone | regulation of translation | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | negative regulation of cell differentiation | signal transduction | response to glucocorticoid | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular