QuickView for Tnrc6a (gene)

Gene Symbol:

TNRC6A Homo sapiens

Full name:

trinucleotide repeat containing 6A

Synonyms:

CAGH26, GW1, GW182, TNRC6, trinucleotide repeat-containing gene 6A protein, CAG repeat protein 26, CTD-2540M10.1, EDIE, EMSY interactor protein, GW182 autoantigen, glycine-tryptophan protein of 182 kDa

Genomic Location:

Chr 16: 24648550-24745049

Description:

This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of t...

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This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

FOXO1_02 ,  PAX4_04 ,  TTTGCAC_MIR19A_MIR19B ,  TGANTCA_AP1_C ,  ACACTCC_MIR122A ,  GNCF_01 ,  TTTTGAG_MIR373 ,  SYATTGTG_UNKNOWN ,  CTTTGCA_MIR527 ,  TEL2_Q6 ,  RNCTGNYNRNCTGNY_UNKNOWN ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  FXR_IR1_Q6 ,  TACTTGA_MIR26A_MIR26B ,  TTGCACT_MIR130A_MIR301_MIR130B ,  FAC1_01 ,  IRF1_Q6 ,  CYTAGCAAY_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  TATAAA_TATA_01 ,  AR_Q6 ,  NFE2_01 ,  STAT3_02 ,  AP1_Q6_01 ,  TAATGTG_MIR323 ,  TITF1_Q3 ,  FOXO3_01 ,  AP1_01 ,  TGCACTG_MIR148A_MIR152_MIR148B ,  LHX3_01 ,  NKX62_Q2 ,  AR_01 ,  BACH2_01 ,  GTTTGTT_MIR495 ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  MGGAAGTG_GABP_B ,  AAAGACA_MIR511 ,  RORA1_01 ,  AATGTGA_MIR23A_MIR23B ,  BACH1_01 ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  CART1_01 ,  SCGGAAGY_ELK1_02 ,  GATA4_Q3 ,  GATA1_05 ,  YTAATTAA_LHX3_01 ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  TGACAGNY_MEIS1_01 ,  CTTTGT_LEF1_Q2 ,  P300_01 ,  SRY_02 ,  ERR1_Q2 ,  FOXO4_02 ,  CACTTTG_MIR520G_MIR520H ,  ACATATC_MIR190 ,  TATTATA_MIR374 ,  RACTNNRTTTNC_UNKNOWN ,  HOX13_01 ,  SF1_Q6 ,  TCF11MAFG_01 ,  TCF11_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-122a ,  Predicted Gene Targets for miR-129 ,  Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-146 ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-190 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-26 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-7 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-495 ,  Predicted Gene Targets for miR-378

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Cytogenetic Map:

16p12.1

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