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QuickView for Tpm-1 (gene)


Gene Symbol:
Tpm1 Mus musculus Mus musculus
Full name:
tropomyosin 1, alpha
Synonyms:
AA986836, AI854628, TM2, Tm3, Tmpa, Tpm-1, alpha-TM, tropomyosin alpha-1 chain, alpha-tropomyosin, tropomyosin-1
Genomic Location:
Chr 9: 66870400-66897020
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

structural molecule activity | actin binding | actin filament binding | protein-containing complex binding | disordered domain specific binding | protein domain specific binding | protein N-terminus binding | cytoskeletal protein binding | identical protein binding | protein heterodimerization activity | protein binding | protein homodimerization activity | protein dimerization activity | structural constituent of cytoskeleton

GO Biological Process

positive regulation of heart contraction | regulation of supramolecular fiber organization | ventricular cardiac muscle tissue morphogenesis | positive regulation of ATPase activity | heart process | positive regulation of blood circulation | actin filament-based process | positive regulation of cellular component organization | ruffle organization | muscle tissue development | regulation of localization | negative regulation of protein complex disassembly | actin cytoskeleton organization | negative regulation of cellular process | regulation of systemic arterial blood pressure by norepinephrine-epinephrine | positive regulation of cell adhesion | regulation of organelle organization | regulation of actin polymerization or depolymerization | cellular process | regulation of cell motility | heart morphogenesis | positive regulation of catalytic activity | negative regulation of cell migration | tissue development | actin filament-based movement | muscle structure development | negative regulation of cell motility | regulation of cellular process | regulation of protein complex assembly | heart contraction | cellular component organization | actin-mediated cell contraction | regulation of systemic arterial blood pressure mediated by a chemical signal | regulation of actin filament length | muscle contraction | muscle organ morphogenesis | response to stimulus | positive regulation of blood pressure | actin-myosin filament sliding | response to stress | regulation of ATPase activity | regulation of heart rate by chemical signal | positive regulation of actin filament bundle assembly | regulation of blood circulation | cardiac muscle tissue development | muscle tissue morphogenesis | supramolecular fiber organization | regulation of heart rate | cardiac ventricle morphogenesis | blood circulation | regulation of cellular component size | regulation of cell adhesion | embryo development | positive regulation of stress fiber assembly | actin filament capping | system development | positive regulation of organelle organization | regulation of actin cytoskeleton organization | multicellular organism development | regulation of actin filament organization | actin filament organization | regulation of catalytic activity | regulation of actomyosin structure organization | regulation of protein complex disassembly | wound healing | regulation of blood pressure | regulation of systemic arterial blood pressure | negative regulation of actin filament polymerization | animal organ morphogenesis | regulation of cell migration | muscle filament sliding | regulation of cellular component movement | positive regulation of hydrolase activity | regulation of heart contraction | chordate embryonic development | striated muscle tissue development | cardiac muscle tissue morphogenesis | regulation of actin filament polymerization | regulation of actin filament depolymerization | positive regulation of cytoskeleton organization | heart development | regulation of locomotion | embryo development ending in birth or egg hatching | striated muscle contraction | regulation of protein depolymerization | positive regulation of molecular function | positive regulation of heart rate by epinephrine | positive regulation of heart rate | negative regulation of protein polymerization | cardiac ventricle development | tissue morphogenesis | response to wounding | ventricular cardiac muscle tissue development | anatomical structure development | structural constituent of cytoskeleton | cell projection organization | positive regulation of supramolecular fiber organization | negative regulation of cytoskeleton organization | negative regulation of protein complex assembly | positive regulation of cellular component biogenesis | animal organ development | negative regulation of cellular component movement | cytoskeleton organization | regulation of stress fiber assembly | negative regulation of actin filament depolymerization | anatomical structure morphogenesis | regulation of actin filament bundle assembly | developmental process | organelle organization | positive regulation of heart rate by epinephrine-norepinephrine | negative regulation of supramolecular fiber organization | cardiac chamber development | in utero embryonic development | regulation of actin filament-based process | cardiac muscle contraction | circulatory system development | negative regulation of locomotion | regulation of cellular component organization | muscle organ development | regulation of cytoskeleton organization | muscle system process | multicellular organismal process

GO Cellular Component

supramolecular fiber | sarcomere | muscle thin filament tropomyosin | cell | myofibril | cytoplasm | striated muscle thin filament | intracellular organelle | actin cytoskeleton | contractile fiber | protein-containing complex | organelle | actin filament | cytoskeleton | intracellular | supramolecular complex