QuickView for Tpm-2 (gene)
- Gene Symbol:
- Tpm2
Mus musculus - Full name:
- tropomyosin 2, beta
- Synonyms:
- Tpm-2, Trop-2, tropomyosin beta chain
- Genomic Location:
- Chr 4: 43527584-43536260
- Description:
-
This gene belongs to the tropomyosin family which encodes proteins that bind to actin filaments and stabilize them by regulating access to actin modifying proteins. The encoded protein is a high molecular weight tropomyosin expressed in slow skeletal muscle. In humans, mutations in this gene are associated with nemaline myopathy, cap disease and di...
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
structural molecule activity | actin binding | actin filament binding | protein-containing complex binding | cytoskeletal protein binding | identical protein binding | protein heterodimerization activity | protein binding | protein homodimerization activity | protein dimerization activity | structural constituent of cytoskeleton
GO Biological Process
actin filament-based process | actin cytoskeleton organization | cellular process | cellular component organization | muscle contraction | supramolecular fiber organization | actin filament organization | structural constituent of cytoskeleton | cytoskeleton organization | organelle organization | muscle system process | multicellular organismal process
GO Cellular Component
supramolecular fiber | sarcomere | muscle thin filament tropomyosin | cell | myofibril | cytoplasm | striated muscle thin filament | intracellular organelle | actin cytoskeleton | contractile fiber | organelle | actin filament | cytoskeleton | intracellular | supramolecular complex
