Transcription%20elongation%20factor%2C%20TFIIS QuickView

Description:: Transcription elongation factor IIS (TFIIS) is a component of RNA polymerase II preinitiation complexes, and is required for preinitiation complex assembly and stability. The association of TFIIS with a promoter depends on functional preinitiation complex components including Mediator and the SAGA complex. TFIIS is composed of three domains: domain 1 forms a 4-helical bundle that appears to bind certain initiation factors; domain 2 forms a 3-helical bundle and is required for Pol II binding; domain 3 forms a zinc ribbon and is essential for stimulation of RNA cleavage.
Taxonomy/Path:: InterPro : Transcription elongation factor, IIS-type / Transcription elongation factor, TFIIS

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