Translins are DNA-binding proteins that specifically recognise consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. They seem to recognise single-sranded DNA ends generated by staggered breaks occuring at recombination hot spots.Translin folds into an alpha-alpha superhelix, consisting of two curved layers of alpha/alpha topology. This structure can be divided into two alpha-bundle subdomains. This entry represents the C-terminal alpha bundle subdomain.