QuickView for Tric (gene)

Gene Symbol:

MARVELD2 Homo sapiens

Full name:

MARVEL domain containing 2

Synonyms:

DFNB49, MARVD2, MRVLDC2, Tric, MARVEL domain-containing protein 2, MARVEL (membrane-associating) domain containing 2, tricellulin

Genomic Location:

Chr 5: 68746699-68775592

Description:

The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transc...

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The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  NKX62_Q2

Cytogenetic Map:

5q13.2

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