QuickView for UBE2C (gene)
- Gene Symbol:
- UBE2C
Homo sapiens - Full name:
- ubiquitin conjugating enzyme E2 C
- Synonyms:
- UBCH10, dJ447F3.2, ubiquitin-conjugating enzyme E2 C, (E3-independent) E2 ubiquitin-conjugating enzyme C, E2 ubiquitin-conjugating enzyme C, cyclin-selective ubiquitin carrier protein, mitotic-specific ubiquitin-conjugating enzyme, ubiquitin conjugating enzyme E2C, ubiquitin-protein ligase C
- Genomic Location:
- Chr 20: 43874662-43879003
- Description:
-
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugati...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
20q13.12
| Transcripts Names |
|---|
| NM_007019 |
| NM_181799 |
| NM_181800 |
| NM_181801 |
| NM_181802 |
| NM_181803 |
| NM_001281742 |
| NM_001281741 |
| NR_104037 |
| NR_104036 |
GO Molecular Function
enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | ubiquitin-like protein ligase binding | ubiquitin-like protein transferase activity | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | ubiquitin-protein transferase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | ubiquitin conjugating enzyme activity | small molecule binding
GO Biological Process
regulation of cell cycle process | positive regulation of cellular component organization | proteolysis | regulation of organelle organization | cellular process | organic substance catabolic process | cellular homeostasis | proteolysis involved in cellular protein catabolic process | regulation of ubiquitin-protein transferase activity | regulation of exit from mitosis | regulation of mitotic nuclear division | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | positive regulation of ubiquitin protein ligase activity | positive regulation of cell cycle phase transition | positive regulation of cellular protein metabolic process | cellular component organization | regulation of mitotic cell cycle phase transition | positive regulation of protein metabolic process | regulation of protein ubiquitination | anaphase-promoting complex-dependent catabolic process | regulation of cell cycle phase transition | exit from mitosis | cellular protein catabolic process | proteasomal protein catabolic process | cellular component assembly | protein modification process | macromolecule modification | nitrogen compound metabolic process | positive regulation of organelle organization | regulation of catalytic activity | free ubiquitin chain polymerization | positive regulation of cell cycle | positive regulation of mitotic cell cycle | cell cycle | protein catabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | protein polymerization | cell division | regulation of cellular protein metabolic process | cellular protein-containing complex assembly | mitotic cell cycle phase transition | regulation of cellular metabolic process | regulation of protein metabolic process | homeostatic process | proteasome-mediated ubiquitin-dependent protein catabolic process | regulation of mitotic cell cycle | positive regulation of molecular function | protein polyubiquitination | protein-containing complex assembly | protein metabolic process | positive regulation of protein modification process | protein ubiquitination | cellular macromolecule catabolic process | positive regulation of mitotic cell cycle phase transition | mitotic cell cycle | nuclear division | metabolic process | ubiquitin-protein transferase activity | organic substance metabolic process | protein modification by small protein conjugation or removal | mitotic nuclear division | positive regulation of exit from mitosis | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | protein K11-linked ubiquitination | ubiquitin recycling | cellular protein metabolic process | organelle organization | positive regulation of cell cycle process | cellular protein modification process | cell cycle phase transition | protein K48-linked ubiquitination | positive regulation of ubiquitin-protein transferase activity | positive regulation of metabolic process | cellular metabolic process | modification-dependent protein catabolic process | positive regulation of protein ubiquitination | regulation of cellular component organization | ubiquitin conjugating enzyme activity | positive regulation of mitotic nuclear division | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | anaphase-promoting complex | nuclear ubiquitin ligase complex | cell | nuclear lumen | cytoplasm | intracellular organelle | ubiquitin ligase complex | protein-containing complex | nucleoplasm | plasma membrane | transferase complex | cullin-RING ubiquitin ligase complex | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cytosol | intracellular | membrane
