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QuickView for UBE2V2;jsessionid=8B9451638ED50BFA88F59AA70FD2232C (gene)


Gene Symbol:
UBE2V2 Homo sapiens Homo sapiens
Full name:
ubiquitin conjugating enzyme E2 V2
Synonyms:
DDVIT1, DDVit-1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2, ubiquitin-conjugating enzyme E2 variant 2, 1 alpha,25-dihydroxyvitamin D3-inducible, DDVit 1, MMS2 homolog, enterocyte differentiation promoting factor, enterocyte differentiation-associated factor 1, enterocyte differentiation-associated factor EDAF-1, enterocyte differentiation-promoting factor 1, methyl methanesulfonate sensitive 2, S. cerevisiae, homolog of, vitamin D3-inducible protein
Genomic Location:
Chr 8: 49083548-49137007
Description:
Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugati...
Orthologs:
Mus musculus Rattus norvegicus C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 8
8q11.21


Transcripts Names
NM_003350
XM_017013808
XM_011517583
Protein Names
A0M8W4
G3V113
Q15819



GO Molecular Function

catalytic activity | ubiquitin-like protein transferase activity | protein binding | ubiquitin-protein transferase activity | transferase activity | ubiquitin conjugating enzyme activity

GO Biological Process

double-strand break repair | positive regulation of cellular component organization | regulation of neurogenesis | regulation of synapse assembly | regulation of cell development | regulation of programmed cell death | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | nervous system development | positive regulation of protein catabolic process | neurogenesis | generation of neurons | regulation of DNA repair | regulation of neuron death | cellular process | protein K63-linked ubiquitination | negative regulation of apoptotic process | postreplication repair | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | regulation of cell differentiation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | cellular aromatic compound metabolic process | positive regulation of response to DNA damage stimulus | positive regulation of cellular protein catabolic process | response to stimulus | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | response to stress | positive regulation of proteolysis involved in cellular protein catabolic process | positive regulation of proteolysis | cellular nitrogen compound metabolic process | double-strand break repair via nonhomologous end joining | protein modification process | regulation of synapse structure or activity | macromolecule modification | DNA repair | regulation of cellular response to stress | negative regulation of neuron apoptotic process | system development | nitrogen compound metabolic process | positive regulation of neuron projection development | multicellular organism development | cellular response to DNA damage stimulus | regulation of neuron differentiation | cellular response to stress | DNA double-strand break processing | positive regulation of cellular metabolic process | regulation of synapse organization | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | positive regulation of cell projection organization | error-free postreplication DNA repair | positive regulation of cell differentiation | cell proliferation | regulation of cellular protein metabolic process | positive regulation of proteasomal protein catabolic process | regulation of cellular metabolic process | regulation of neuron apoptotic process | regulation of protein metabolic process | positive regulation of synapse assembly | regulation of proteasomal ubiquitin-dependent protein catabolic process | protein polyubiquitination | protein metabolic process | protein ubiquitination | DNA metabolic process | anatomical structure development | positive regulation of neurogenesis | metabolic process | positive regulation of cell development | positive regulation of ubiquitin-dependent protein catabolic process | ubiquitin-protein transferase activity | regulation of protein catabolic process | negative regulation of programmed cell death | regulation of proteasomal protein catabolic process | regulation of response to DNA damage stimulus | nucleobase-containing compound metabolic process | positive regulation of cellular component biogenesis | organic substance metabolic process | protein modification by small protein conjugation or removal | cellular protein metabolic process | regulation of nervous system development | regulation of developmental process | positive regulation of DNA metabolic process | developmental process | cellular protein modification process | heterocycle metabolic process | positive regulation of metabolic process | positive regulation of neuron differentiation | regulation of cell projection organization | cellular metabolic process | regulation of cell death | negative regulation of cell death | regulation of ubiquitin-dependent protein catabolic process | regulation of cellular component organization | ubiquitin conjugating enzyme activity | positive regulation of DNA repair | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | vesicle | transferase complex | ubiquitin conjugating enzyme complex | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | membrane-enclosed lumen | UBC13-MMS2 complex | intracellular