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QuickView for UBE2W;jsessionid=753345F2F49CF6930C0E50EA4B45577D (gene)


Gene Symbol:
UBE2W Homo sapiens Homo sapiens
Full name:
ubiquitin conjugating enzyme E2 W
Synonyms:
UBC-16, UBC16, ubiquitin-conjugating enzyme E2 W, E2 ubiquitin-conjugating enzyme W, N-terminal E2 ubiquitin-conjugating enzyme, N-terminus-conjugating E2, ubiquitin carrier protein W, ubiquitin conjugating enzyme E2 W (putative), ubiquitin conjugating enzyme E2W (putative), ubiquitin-conjugating enzyme 16, ubiquitin-conjugating enzyme 2W, ubiquitin-protein ligase W
Genomic Location:
Chr 8: 74865394-74953664
Description:
This gene encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA ...
Orthologs:
Mus musculus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio Rattus norvegicus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
TGGAAA_NFAT_Q4_01 CACTGTG_MIR128A_MIR128B AGCYRWTTC_UNKNOWN TCANNTGAY_SREBP1_01 CAGGTCC_MIR492 AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D CTATGCA_MIR153 TTTGTAG_MIR520D YATTNATC_UNKNOWN TAGCTTT_MIR9
Cytogenetic Map:
chr 8
8q21.11





GO Molecular Function

enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | ubiquitin-like protein ligase binding | ubiquitin-like protein transferase activity | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | ubiquitin protein ligase binding | ubiquitin-protein transferase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | ubiquitin conjugating enzyme activity | small molecule binding

GO Biological Process

proteolysis | response to misfolded protein | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | catabolic process | organic cyclic compound metabolic process | response to topologically incorrect protein | cellular aromatic compound metabolic process | cellular response to topologically incorrect protein | response to stimulus | response to stress | cellular protein catabolic process | cellular nitrogen compound metabolic process | proteasomal protein catabolic process | protein modification process | macromolecule modification | DNA repair | nitrogen compound metabolic process | protein monoubiquitination | cellular response to DNA damage stimulus | cellular response to stress | protein catabolic process | protein modification by small protein conjugation | proteasome-mediated ubiquitin-dependent protein catabolic process | protein polyubiquitination | protein metabolic process | response to organic substance | protein ubiquitination | DNA metabolic process | cellular macromolecule catabolic process | metabolic process | ubiquitin-protein transferase activity | protein quality control for misfolded or incompletely synthesized proteins | nucleobase-containing compound metabolic process | organic substance metabolic process | protein modification by small protein conjugation or removal | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | protein K11-linked ubiquitination | cellular protein metabolic process | cellular protein modification process | heterocycle metabolic process | cellular response to misfolded protein | cellular metabolic process | cellular response to organic substance | modification-dependent protein catabolic process | ubiquitin conjugating enzyme activity | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular