QuickView for UBR7 (gene)

Gene Symbol:

UBR7 Homo sapiens

Full name:

ubiquitin protein ligase E3 component n-recognin 7 (putative)

Synonyms:

C14orf130, putative E3 ubiquitin-protein ligase UBR7, N-recognin-7, RING-type E3 ubiquitin transferase UBR7

Genomic Location:

Chr 14: 92743154-92765314

Description:

This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteaso...

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This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E2F4DP1_01 ,  TTTGTAG_MIR520D ,  GTACTGT_MIR101 ,  E2F_Q6 ,  E2F1_Q6_01 ,  GAGCTGG_MIR337 ,  E2F_Q4 ,  CATRRAGC_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  E2F1DP2_01 ,  E2F1DP1_01 ,  GTGCCTT_MIR506 ,  E2F1DP1RB_01 ,  GTCNYYATGR_UNKNOWN ,  E2F_02 ,  E2F1_Q3 ,  E2F4DP2_01 ,  E2F1_Q6 ,  SGCGSSAAA_E2F1DP2_01 ,  OLF1_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-188 ,  Predicted Gene Targets for miR-376c ,  Predicted Gene Targets for miR-543

Cytogenetic Map:

14q32.12

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