QuickView for UGGT2 (gene)
- Gene Symbol:
- UGGT2
Homo sapiens - Full name:
- UDP-glucose glycoprotein glucosyltransferase 2
- Synonyms:
- HUGT2, UGCGL2, UGT2, UDP-glucose:glycoprotein glucosyltransferase 2, UDP-Glc:glycoprotein glucosyltransferase 2, UDP-glucose ceramide glucosyltransferase-like 1, UDP-glucose ceramide glucosyltransferase-like 2
- Genomic Location:
- Chr 13: 95251835-95503638
- Description:
-
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
13q32.1
GO Molecular Function
UDP-glucosyltransferase activity | UDP-glycosyltransferase activity | unfolded protein binding | catalytic activity | glucosyltransferase activity | transferase activity, transferring glycosyl groups | protein binding | UDP-glucose:glycoprotein glucosyltransferase activity | transferase activity, transferring hexosyl groups | transferase activity
GO Biological Process
response to endoplasmic reticulum stress | proteolysis | peptidyl-amino acid modification | response to misfolded protein | ER-associated misfolded protein catabolic process | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | endoplasmic reticulum mannose trimming | glycoprotein biosynthetic process | catabolic process | UDP-glucosylation | organic cyclic compound metabolic process | response to topologically incorrect protein | cellular aromatic compound metabolic process | protein N-linked glycosylation via asparagine | cellular response to topologically incorrect protein | response to stimulus | UDP-glucose metabolic process | response to stress | protein deglycosylation | cellular protein catabolic process | cellular nitrogen compound metabolic process | proteasomal protein catabolic process | carbohydrate derivative biosynthetic process | protein modification process | macromolecule glycosylation | cellular biosynthetic process | macromolecule modification | response to nitrogen compound | nitrogen compound metabolic process | phosphorus metabolic process | cellular response to stress | protein catabolic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | biosynthetic process | ERAD pathway | protein metabolic process | response to organic substance | cellular macromolecule catabolic process | metabolic process | protein quality control for misfolded or incompletely synthesized proteins | nucleobase-containing compound metabolic process | UDP-glucose:glycoprotein glucosyltransferase activity | nucleotide-sugar metabolic process | organic substance metabolic process | organonitrogen compound catabolic process | cellular protein metabolic process | protein N-linked glycosylation | cellular macromolecule biosynthetic process | cellular protein modification process | carbohydrate derivative metabolic process | response to organonitrogen compound | heterocycle metabolic process | protein glycosylation | glycosylation | cellular response to misfolded protein | cellular metabolic process | cellular response to organic substance | glycoprotein metabolic process | protein alpha-1,2-demannosylation | macromolecule metabolic process
GO Cellular Component
endoplasmic reticulum-Golgi intermediate compartment | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | protein-containing complex | endomembrane system | endoplasmic reticulum lumen | membrane-bounded organelle | organelle | membrane-enclosed lumen | intracellular | endoplasmic reticulum quality control compartment
