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QuickView for UGT1A1 (gene)

Gene Symbol:
UGT1A1 Homo sapiens Homo sapiens
Full name:
UDP glucuronosyltransferase family 1 member A1
BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT 1-1, UGT1, UGT1A, UDP-glucuronosyltransferase 1-1, UDP glucuronosyltransferase 1 family, polypeptide A1, UDP glycosyltransferase 1 family, polypeptide A1, UDP-glucuronosyltransferase 1-A, UDP-glucuronosyltransferase 1A1, UGT-1A, UGT1*1, UGT1-01, UGT1.1, bilirubin UDP-glucuronosyltranserase, bilirubin UDP-glucuronosyltransferase 1-1, bilirubin UDP-glucuronosyltransferase isozyme 1, bilirubin-specific UDPGT isozyme 1
Genomic Location:
Chr 2: 234333658-234346684
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique...
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Danio rerio Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 2

Transcripts Names
Protein Names

GO Molecular Function

isoprenoid binding | retinoid binding | carboxylic acid binding | enzyme binding | lipid binding | enzyme inhibitor activity | UDP-glycosyltransferase activity | molecular function regulator | catalytic activity | anion binding | identical protein binding | transferase activity, transferring glycosyl groups | protein heterodimerization activity | ion binding | organic cyclic compound binding | protein binding | protein homodimerization activity | protein dimerization activity | transferase activity, transferring hexosyl groups | transferase activity | enzyme regulator activity | retinoic acid binding | steroid binding | glucuronosyltransferase activity | organic acid binding | small molecule binding

GO Biological Process

response to extracellular stimulus | response to nutrient levels | response to lipopolysaccharide | response to hormone | defense response | response to drug | xenobiotic catabolic process | benzene-containing compound metabolic process | estrogen metabolic process | response to antibiotic | cellular process | organic substance catabolic process | response to estradiol | heme metabolic process | porphyrin-containing compound metabolic process | regeneration | cellular response to lipid | regulation of metabolic process | xenobiotic metabolic process | catabolic process | hepaticobiliary system development | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular lipid metabolic process | heme catabolic process | response to stimulus | enzyme inhibitor activity | monocarboxylic acid metabolic process | cellular response to xenobiotic stimulus | response to stress | flavone metabolic process | response to starvation | response to alcohol | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | cellular response to toxic substance | cellular response to ethanol | cellular response to organic cyclic compound | negative regulation of metabolic process | cofactor metabolic process | regulation of steroid metabolic process | molecular function regulator | response to ethanol | cellular response to hormone stimulus | retinoid metabolic process | response to external biotic stimulus | system development | nitrogen compound metabolic process | cellular response to antibiotic | multicellular organism development | negative regulation of catalytic activity | antibiotic metabolic process | regulation of catalytic activity | lipid metabolic process | regulation of hormone levels | response to lipid | liver development | monosaccharide metabolic process | small molecule metabolic process | response to corticosteroid | response to nutrient | glucuronate metabolic process | acute-phase response | cellular response to glucocorticoid stimulus | flavonoid metabolic process | carbohydrate metabolic process | response to toxic substance | response to xenobiotic stimulus | cellular response to corticosteroid stimulus | cellular response to drug | response to bacterium | retinoic acid metabolic process | inflammatory response | aromatic compound catabolic process | drug metabolic process | carboxylic acid metabolic process | response to organic substance | gland development | biphenyl metabolic process | anatomical structure development | negative regulation of lipid metabolic process | metabolic process | biphenyl catabolic process | bilirubin conjugation | organic substance metabolic process | pigment metabolic process | animal organ development | diterpenoid metabolic process | cellular glucuronidation | cellular response to steroid hormone stimulus | organonitrogen compound catabolic process | cellular response to estradiol stimulus | steroid metabolic process | negative regulation of molecular function | response to organic cyclic compound | organic acid metabolic process | enzyme regulator activity | hormone metabolic process | response to biotic stimulus | isoprenoid metabolic process | developmental process | negative regulation of steroid metabolic process | flavonoid glucuronidation | heterocycle metabolic process | regulation of lipid metabolic process | acute inflammatory response | cellular metabolic process | cellular response to organic substance | response to steroid hormone | xenobiotic glucuronidation | response to other organism | animal organ regeneration | response to glucocorticoid | multicellular organismal process

GO Cellular Component

endoplasmic reticulum chaperone complex | integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | plasma membrane | cytochrome complex | integral component of plasma membrane | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane | intrinsic component of plasma membrane