QuickView for Ube2T (gene)
- Gene Symbol:
- UBE2T
Homo sapiens - Full name:
- ubiquitin conjugating enzyme E2 T
- Synonyms:
- FANCT, HSPC150, PIG50, ubiquitin-conjugating enzyme E2 T, E2 ubiquitin-conjugating enzyme T, HSPC150 protein similar to ubiquitin-conjugating enzyme, cell proliferation-inducing gene 50 protein, ubiquitin carrier protein T, ubiquitin conjugating enzyme E2T, ubiquitin-conjugating enzyme E2T (putative), ubiquitin-protein ligase T
- Genomic Location:
- Chr 1: 200567408-200577707
- Description:
-
The protein encoded by this gene catalyzes the covalent attachment of ubiquitin to protein substrates. Defects in this gene have been associated with Fanconi anemia of complementation group T. Two transcript variants encoding different isoforms have been found for this gene.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
1q32.1
GO Molecular Function
enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | chromatin binding | ATP binding | ubiquitin-like protein ligase binding | ubiquitin-like protein transferase activity | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | ubiquitin protein ligase binding | ubiquitin-protein transferase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | ubiquitin conjugating enzyme activity | small molecule binding
GO Biological Process
interstrand cross-link repair | cellular process | protein K63-linked ubiquitination | protein K27-linked ubiquitination | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | response to stress | cellular nitrogen compound metabolic process | protein modification process | macromolecule modification | protein K6-linked ubiquitination | DNA repair | nitrogen compound metabolic process | protein monoubiquitination | cellular response to DNA damage stimulus | cellular response to stress | protein modification by small protein conjugation | protein K29-linked ubiquitination | protein polyubiquitination | protein metabolic process | protein ubiquitination | DNA metabolic process | protein autoubiquitination | metabolic process | ubiquitin-protein transferase activity | nucleobase-containing compound metabolic process | organic substance metabolic process | protein modification by small protein conjugation or removal | protein K11-linked ubiquitination | cellular protein metabolic process | cellular protein modification process | heterocycle metabolic process | protein K48-linked ubiquitination | cellular metabolic process | ubiquitin conjugating enzyme activity | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | nucleolus | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
