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QuickView for VAMP8;jsessionid=294EDDCCC7989D0B34A361E2CB0E8FAD (gene)


Gene Symbol:
VAMP8 Homo sapiens Homo sapiens
Full name:
vesicle associated membrane protein 8
Synonyms:
EDB, VAMP-8, vesicle-associated membrane protein 8, vesicle-associated membrane protein 8 (endobrevin)
Genomic Location:
Chr 2: 85658228-85662665
Description:
This gene encodes an integral membrane protein that belongs to the synaptobrevin/vesicle-associated membrane protein subfamily of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). The encoded protein is involved in the fusion of synaptic vesicles with the presynaptic membrane.
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Danio rerio Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 2
2p11.2


Transcripts Names
NM_003761
XM_017005170
Protein Names
Q9BV40
Q6IB09
Q53SP9
B8ZZT4
O60625



GO Molecular Function

channel regulator activity | ion channel inhibitor activity | chloride channel regulator activity | molecular function regulator | channel inhibitor activity | chloride channel inhibitor activity | protein binding

GO Biological Process

positive regulation of immune response | regulation of histamine secretion by mast cell | exocytosis | antigen processing and presentation | neutrophil activation | regulation of cellular localization | regulation of localization | macroautophagy | establishment of localization | regulation of immune system process | negative regulation of cellular process | regulation of protein localization to membrane | membrane organization | cellular process | secretion | channel regulator activity | leukocyte degranulation | localization | protein transport | positive regulation of immune effector process | macromolecule localization | negative regulation of secretion | membrane docking | interspecies interaction between organisms | regulation of immune response | regulation of cellular process | leukocyte activation | catabolic process | organelle localization | cellular component organization | entry into host cell | regulation of mast cell degranulation | viral life cycle | response to stimulus | regulation of cellular protein localization | neutrophil degranulation | ion channel inhibitor activity | positive regulation of immune system process | leukocyte activation involved in immune response | positive regulation of mast cell degranulation | positive regulation of cell activation | cellular localization | secretion by cell | positive regulation of hormone secretion | negative regulation of transport | chloride channel regulator activity | regulation of intracellular transport | molecular function regulator | positive regulation of exocytosis | negative regulation of secretion by cell | channel inhibitor activity | positive regulation of inflammatory response | leukocyte mediated immunity | regulation of hormone levels | regulation of hormone secretion | antigen processing and presentation of exogenous peptide antigen via MHC class I | viral entry into host cell | positive regulation of secretion | organic substance transport | regulation of mast cell activation | peptide transport | vesicle-mediated transport | chloride channel inhibitor activity | regulated exocytosis | autophagosome membrane docking | autophagy | positive regulation of regulated secretory pathway | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | positive regulation of transport | viral process | mucus secretion | antigen processing and presentation of exogenous antigen | regulation of exocytosis | antigen processing and presentation of peptide antigen via MHC class I | metabolic process | regulation of protein localization to plasma membrane | positive regulation of leukocyte activation | regulation of body fluid levels | amide transport | regulation of vesicle-mediated transport | regulation of secretion | body fluid secretion | immune response | positive regulation of mast cell activation | positive regulation of ion transport | regulation of cell activation | positive regulation of histamine secretion by mast cell | establishment of protein localization | regulation of regulated secretory pathway | positive regulation of intracellular transport | cell activation | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | regulation of cell communication | protein localization | protein-containing complex disassembly | regulation of ion transport | eosinophil degranulation | regulation of transport | neutrophil mediated immunity | antigen processing and presentation of peptide antigen | immune system process | cellular metabolic process | regulation of protein localization | regulation of inflammatory response | autophagosome maturation | positive regulation of signaling | carbohydrate derivative transport | regulation of signaling | multicellular organismal process

GO Cellular Component

secretory granule | integral component of membrane | intracellular membrane-bounded organelle | early endosome membrane | late endosome | endocytic vesicle membrane | clathrin-coated vesicle membrane | organelle membrane | clathrin-coated vesicle | tertiary granule | cytoplasmic vesicle | mucin granule | cell | late endosome membrane | intrinsic component of membrane | cytoplasm | intracellular organelle | secretory granule membrane | endosome membrane | protein-containing complex | recycling endosome | secretory vesicle | phagocytic vesicle membrane | endomembrane system | plasma membrane | azurophil granule membrane | vacuole | vesicle | perinuclear region of cytoplasm | extracellular exosome | specific granule | lytic vacuole | SNARE complex | endosome | extracellular region | coated vesicle membrane | membrane-bounded organelle | extracellular vesicle | organelle | recycling endosome membrane | vesicle membrane | lysosome | extracellular space | cell periphery | azurophil granule | early endosome | tertiary granule membrane | cytosol | intracellular vesicle | endocytic vesicle | intracellular | specific granule membrane | lysosomal membrane | membrane | cytoplasmic vesicle membrane | phagocytic vesicle | vacuolar membrane | coated vesicle