QuickView for VAV2 (gene)

Gene Symbol:

VAV2 Homo sapiens

Full name:

vav guanine nucleotide exchange factor 2

Synonyms:

VAV-2, guanine nucleotide exchange factor VAV2, vav 2 guanine nucleotide exchange factor, vav 2 oncogene

Genomic Location:

Chr 9: 135616837-135847226

Description:

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MAF_Q6 ,  GCTCTTG_MIR335 ,  TTGCCAA_MIR182 ,  CTTTGT_LEF1_Q2 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-335 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-410

Cytogenetic Map:

9q34.2

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