Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for VCAM1 (gene)


Gene Symbol:
VCAM1 Homo sapiens Homo sapiens
Full name:
vascular cell adhesion molecule 1
Synonyms:
CD106, INCAM-100, vascular cell adhesion protein 1, CD106 antigen
Genomic Location:
Chr 1: 100957885-100977189
Description:
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced tran...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Canis lupus familiaris Gallus gallus Pan troglodytes Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 1
1p21.2


Transcripts Names
NM_001078
NM_080682
NM_001199834
Protein Names
Q6NUP8
E9PDD1
A8K6R7
B4DKS4
P19320



GO Molecular Function

protein-containing complex binding | signaling receptor binding | catalytic activity | integrin binding | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | cell adhesion molecule binding | primary amine oxidase activity | protein binding | oxidoreductase activity, acting on the CH-NH2 group of donors | oxidoreductase activity

GO Biological Process

response to extracellular stimulus | response to radiation | response to nutrient levels | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | extracellular structure organization | response to cytokine | cell motility | response to lipopolysaccharide | intracellular signal transduction | cell-substrate adhesion | regulation of immune system process | response to metal ion | cellular response to tumor necrosis factor | positive regulation of lymphocyte activation | cell differentiation | defense response | nervous system development | response to drug | neurogenesis | positive regulation of cell adhesion | generation of neurons | B cell differentiation | response to antibiotic | cellular process | lymphocyte differentiation | localization | immune system development | response to hypoxia | membrane docking | response to growth factor | response to inorganic substance | interspecies interaction between organisms | autonomic nervous system development | regulation of immune response | regulation of cellular process | leukocyte activation | leukocyte tethering or rolling | interferon-gamma-mediated signaling pathway | cellular component organization | cellular response to interferon-gamma | response to stimulus | cellular response to vascular endothelial growth factor stimulus | positive regulation of immune system process | response to stress | positive regulation of lymphocyte proliferation | regulation of cell proliferation | positive regulation of cell-cell adhesion | positive regulation of cell activation | response to alcohol | response to molecule of bacterial origin | positive regulation of T cell activation | extracellular matrix organization | hemopoiesis | amine metabolic process | regulation of cell adhesion | cell chemotaxis | response to ethanol | leukocyte migration | leukocyte differentiation | locomotion | positive regulation of mononuclear cell proliferation | response to nicotine | response to external biotic stimulus | system development | response to oxygen levels | nitrogen compound metabolic process | multicellular organism development | cell migration | regulation of T cell activation | response to lipid | regulation of lymphocyte activation | cardiac neuron differentiation | cytokine-mediated signaling pathway | cardiocyte differentiation | response to nutrient | second-messenger-mediated signaling | cellular response to cytokine stimulus | B cell activation | innervation | positive regulation of T cell proliferation | response to toxic substance | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | response to bacterium | cell communication | inflammatory response | heart development | positive regulation of cell proliferation | response to zinc ion | primary amine oxidase activity | viral process | lymphocyte activation | calcium-mediated signaling | neuron differentiation | chronic inflammatory response | response to organic substance | leukocyte adhesion to vascular endothelial cell | anatomical structure development | cell surface receptor signaling pathway | leukocyte cell-cell adhesion | metabolic process | positive regulation of leukocyte activation | oxidation-reduction process | cell adhesion | immune response | organic substance metabolic process | oxidoreductase activity, acting on the CH-NH2 group of donors | animal organ development | membrane to membrane docking | nerve development | regulation of cell activation | cell-cell adhesion | response to interferon-gamma | cell activation | signaling | cell-matrix adhesion | regulation of T cell proliferation | response to biotic stimulus | developmental process | cellular extravasation | calcium-mediated signaling using intracellular calcium source | regulation of cell-cell adhesion | innate immune response | cell-cell adhesion via plasma-membrane adhesion molecules | acute inflammatory response | immune system process | hematopoietic or lymphoid organ development | response to tumor necrosis factor | cellular response to organic substance | oxidoreductase activity | circulatory system development | aging | chemotaxis | positive regulation of leukocyte cell-cell adhesion | response to ionizing radiation | response to other organism | signal transduction | cellular response to growth factor stimulus | multicellular organismal process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | sarcolemma | cytoplasmic vesicle | actin-based cell projection | cell | plasma membrane protein complex | intrinsic component of membrane | alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex | external side of plasma membrane | cytoplasm | intracellular organelle | actin cytoskeleton | endoplasmic reticulum | apical part of cell | Golgi apparatus | protein-containing complex | cell projection | endomembrane system | plasma membrane | vesicle | podosome | extracellular exosome | integral component of plasma membrane | endosome | extracellular region | microvillus | membrane-bounded organelle | extracellular vesicle | filopodium | organelle | extracellular space | cell periphery | early endosome | intracellular vesicle | cell surface | cytoskeleton | intracellular | membrane | intrinsic component of plasma membrane