QuickView for VDAC2;jsessionid=64EE3FB6B9C8693E79AC5B369EF2B336 (gene)

Gene Symbol:

VDAC2 Homo sapiens

Full name:

voltage dependent anion channel 2

Synonyms:

POR, voltage-dependent anion-selective channel protein 2, outer mitochondrial membrane protein porin 2

Genomic Location:

Chr 10: 76640569-76661212

Description:

This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity...

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This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFMUE1_Q6 ,  PU1_Q6 ,  GATA1_01 ,  PEA3_Q6 ,  IRF1_Q6 ,  TGACCTY_ERR1_Q2 ,  YYCATTCAWW_UNKNOWN ,  ETS2_B ,  GTTTGTT_MIR495 ,  GGGCGGR_SP1_Q6 ,  CAGCAGG_MIR370 ,  RGAGGAARY_PU1_Q6 ,  E2F_Q2 ,  AAAGGAT_MIR501 ,  ERR1_Q2 ,  TGACCTTG_SF1_Q6 ,  SF1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-132 ,  Predicted Gene Targets for miR-138 ,  Predicted Gene Targets for miR-370 ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-495

Cytogenetic Map:

10q22.2

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