QuickView for VEGF D (gene)

Gene Symbol:

VEGFD Homo sapiens

Full name:

vascular endothelial growth factor D

Synonyms:

FIGF, VEGF-D, vascular endothelial growth factor D, c-fos induced growth factor (vascular endothelial growth factor D)

Genomic Location:

Chr X: 15273639-15312498

Description:

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 ...

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The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AP1_C ,  TGANTCA_AP1_C ,  RYTTCCTG_ETS2_B ,  STAT6_01 ,  WTGAAAT_UNKNOWN ,  NFE2_01 ,  AP1FJ_Q2 ,  NF1_Q6 ,  GTATGAT_MIR154_MIR487 ,  STAT5A_03 ,  TGCCAAR_NF1_Q6 ,  NF1_Q6_01 ,  MEIS1AHOXA9_01 ,  GATA4_Q3 ,  TGCTTTG_MIR330 ,  AP1_Q2 ,  AACTTT_UNKNOWN

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-330

Cytogenetic Map:

Xp22.2

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