QuickView for VPS34 (gene)
- Gene Symbol:
- VPS34
Saccharomyces cerevisiae - Full name:
- Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p
- Synonyms:
- END12, PEP15, VPL7, VPS34, VPS34, Vps34, VPT29, YLR240W
- Genomic Location:
- Chr XII: 617535-620162
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Schizosaccharomyces pombe , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | phosphatidylinositol 3-kinase activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | 1-phosphatidylinositol-3-kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
positive regulation of macromolecule biosynthetic process | regulation of cellular localization | intracellular signal transduction | regulation of localization | macroautophagy | phosphatidylinositol metabolic process | establishment of localization | regulation of autophagy | phosphatidylinositol-3-phosphate biosynthetic process | phospholipid metabolic process | positive regulation of cellular biosynthetic process | cellular process | localization | protein transport | macromolecule localization | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | cellular component organization | cellular lipid metabolic process | response to stimulus | regulation of cellular protein localization | phosphatidylinositol-mediated signaling | regulation of macroautophagy | positive regulation of RNA biosynthetic process | cellular component assembly | protein modification process | cellular biosynthetic process | macromolecule modification | regulation of nucleic acid-templated transcription | organelle assembly | nitrogen compound metabolic process | autophagosome organization | phosphorus metabolic process | lipid metabolic process | regulation of gene expression | organic substance transport | organophosphate metabolic process | positive regulation of cellular metabolic process | phospholipid biosynthetic process | regulation of nitrogen compound metabolic process | peptide transport | autophagy of peroxisome | vesicle-mediated transport | regulation of transcription by RNA polymerase II | phosphatidylinositol 3-kinase activity | biosynthetic process | regulation of transcription elongation from RNA polymerase II promoter | phosphorylation | lipid biosynthetic process | inositol lipid-mediated signaling | protein phosphorylation | phosphate-containing compound metabolic process | vacuole organization | autophagy | lipid phosphorylation | cell communication | regulation of cellular metabolic process | lipid modification | glycerolipid metabolic process | regulation of RNA metabolic process | protein metabolic process | autophagosome assembly | glycerophospholipid biosynthetic process | 1-phosphatidylinositol-3-kinase activity | import into cell | metabolic process | positive regulation of transcription elongation from RNA polymerase II promoter | regulation of RNA biosynthetic process | amide transport | endocytosis | protein kinase activity | organic substance metabolic process | phosphatidylinositol biosynthetic process | positive regulation of autophagy | establishment of protein localization | regulation of DNA-templated transcription, elongation | positive regulation of macroautophagy | signaling | regulation of transcription, DNA-templated | protein localization | cellular protein metabolic process | phosphatidylinositol phosphorylation | glycerophospholipid metabolic process | kinase activity | positive regulation of DNA-templated transcription, elongation | regulation of protein localization by the Cvt pathway | organelle organization | cellular protein modification process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | cellular metabolic process | regulation of protein localization | signal transduction | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | phosphatidylinositol 3-kinase complex | extrinsic component of membrane | organelle membrane | peroxisome | cytoplasmic vesicle | cell | phosphatidylinositol 3-kinase complex, class III, type II | organelle membrane contact site | cytoplasm | intracellular organelle | endosome membrane | Golgi apparatus | phagophore assembly site | protein-containing complex | endomembrane system | fungal-type vacuole | nuclear envelope | vacuole | vesicle | transferase complex | lytic vacuole | endosome | membrane-bounded organelle | nucleus | organelle | fungal-type vacuole membrane | phosphatidylinositol 3-kinase complex, class III | nuclear pore | cytosol | storage vacuole | intracellular vesicle | nucleus-vacuole junction | intracellular | membrane | phosphatidylinositol 3-kinase complex, class III, type I | vacuolar membrane
