QuickView for VPS39 (gene)

Gene Symbol:

VPS39 Homo sapiens

Full name:

VPS39, HOPS complex subunit

Synonyms:

TLP, VAM6, hVam6p, vam6/Vps39-like protein, TRAP1-like protein, vacuolar protein sorting 39 homolog

Genomic Location:

Chr 15: 40238191-40287794

Description:

This gene encodes a protein that may promote clustering and fusion of late endosomes and lysosomes. The protein may also act as an adaptor protein that modulates the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway. Alternative splicing results in multiple transcript varia...

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This gene encodes a protein that may promote clustering and fusion of late endosomes and lysosomes. The protein may also act as an adaptor protein that modulates the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CGGAARNGGCNG_UNKNOWN ,  CCCAGAG_MIR326 ,  RYTTCCTG_ETS2_B ,  STAT6_02 ,  GGGCGGR_SP1_Q6 ,  ETS1_B

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-326

Cytogenetic Map:

15q15.1

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