QuickView for VPS4 (gene)
- Gene Symbol:
- VPS4
Saccharomyces cerevisiae - Full name:
- AAA-type ATPase that is regulated by Vta1p; required for late endosome to vacuole transport; catalyzes the release of an endosomal membrane-associated class E VPS protein complex; regulates cellular sterol metabolism
- Synonyms:
- CSC1, DID6, END13, GRD13, VPL4, Vps4, VPS4, vps4, VPS4, VPT10, YPR173C
- Genomic Location:
- Chr XVI: 886520-887833
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | protein dimerization activity | hydrolase activity, acting on acid anhydrides | microtubule-severing ATPase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
protein homooligomerization | macroautophagy | establishment of localization | microtubule cytoskeleton organization | membrane organization | intracellular transport | microtubule-based process | sterol metabolic process | cellular process | endosome transport via multivesicular body sorting pathway | localization | protein transport | macromolecule localization | endomembrane system organization | establishment of localization in cell | catabolic process | organic cyclic compound metabolic process | cellular component organization | endosomal transport | vacuolar transport | protein retention in Golgi apparatus | supramolecular fiber organization | cellular localization | cellular component assembly | organic hydroxy compound metabolic process | protein complex oligomerization | lipid metabolic process | organic substance transport | peptide transport | vesicle-mediated transport | protein localization to organelle | autophagy | maintenance of protein location | cytoplasmic microtubule organization | microtubule severing | protein-containing complex assembly | protein localization to Golgi apparatus | late endosome to vacuole transport via multivesicular body sorting pathway | metabolic process | cellular protein localization | amide transport | intralumenal vesicle formation | organic substance metabolic process | maintenance of protein location in cell | cytoskeleton organization | late endosome to vacuole transport | establishment of protein localization | vesicle organization | vesicle budding from membrane | microtubule-severing ATPase activity | steroid metabolic process | protein localization | cellular macromolecule localization | endosome organization | organelle organization | cellular metabolic process | multivesicular body sorting pathway | maintenance of location in cell
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | endosome membrane | endomembrane system | vesicle | endosome | membrane-bounded organelle | nucleus | organelle | intracellular vesicle | intracellular | membrane
