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QuickView for Vimentin (gene)


Gene Symbol:
VIM Homo sapiens Homo sapiens
Full name:
vimentin
Synonyms:
vimentin
Genomic Location:
Chr 10: 17311304-17319598
Description:
This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and choles...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 10
10p13





GO Molecular Function

structural molecule activity | keratin filament binding | nucleic acid binding | protein-containing complex binding | protein domain specific binding | identical protein binding | scaffold protein binding | organic cyclic compound binding | protein binding | structural constituent of eye lens | structural constituent of cytoskeleton | intermediate filament binding | heterocyclic compound binding | protein C-terminus binding | RNA binding | double-stranded RNA binding

GO Biological Process

SMAD protein signal transduction | positive regulation of macromolecule biosynthetic process | actin filament-based process | response to cytokine | regulation of neurogenesis | regulation of cell development | positive regulation of collagen metabolic process | intermediate filament organization | eye development | astrocyte development | negative regulation of cellular process | cell differentiation | defense response | nervous system development | neurogenesis | generation of neurons | positive regulation of cellular biosynthetic process | cellular process | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | tissue development | regulation of cell differentiation | interspecies interaction between organisms | actin filament-based movement | regulation of mRNA stability | regulation of cellular process | regulation of metabolic process | gliogenesis | positive regulation of translation | positive regulation of cellular protein metabolic process | epithelium development | cellular component organization | actin-mediated cell contraction | cellular response to interferon-gamma | muscle contraction | response to stimulus | positive regulation of protein metabolic process | actin-myosin filament sliding | response to stress | posttranscriptional regulation of gene expression | negative regulation of neuron projection development | epithelial cell development | supramolecular fiber organization | system development | multicellular organism development | regulation of collagen biosynthetic process | regulation of neuron differentiation | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | cytokine-mediated signaling pathway | muscle filament sliding | regulation of RNA stability | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | glial cell differentiation | sensory organ development | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | astrocyte differentiation | regulation of collagen metabolic process | regulation of protein metabolic process | regulation of RNA metabolic process | viral process | response to organic substance | negative regulation of cell projection organization | anatomical structure development | structural constituent of cytoskeleton | cell surface receptor signaling pathway | lens fiber cell development | intermediate filament-based process | immune response | animal organ development | regulation of mRNA catabolic process | negative regulation of neuron differentiation | cytoskeleton organization | Bergmann glial cell differentiation | response to interferon-gamma | camera-type eye development | signaling | glial cell development | cell development | regulation of nervous system development | regulation of developmental process | developmental process | organelle organization | intermediate filament cytoskeleton organization | innate immune response | epithelial cell differentiation | central nervous system development | positive regulation of metabolic process | regulation of cell projection organization | immune system process | positive regulation of collagen biosynthetic process | cellular response to organic substance | lens fiber cell differentiation | regulation of translation | negative regulation of cell development | negative regulation of cell differentiation | regulation of cellular component organization | lens development in camera-type eye | muscle system process | signal transduction | positive regulation of gene expression | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

intermediate filament | supramolecular fiber | intracellular membrane-bounded organelle | neuron projection | polysome | adherens junction | peroxisome | focal adhesion | cytoplasmic vesicle | cell | nuclear lumen | cytoplasm | cell-substrate junction | intracellular organelle | intermediate filament cytoskeleton | protein-containing complex | cell projection | plasma membrane | cell leading edge | ribonucleoprotein complex | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | cell periphery | membrane-enclosed lumen | cell-substrate adherens junction | nuclear matrix | cytosol | intracellular vesicle | cytoskeleton | endocytic vesicle | intracellular | cell junction | membrane | supramolecular complex | nuclear periphery | phagocytic vesicle