QuickView for WFIKKN1;jsessionid=C11836744F93C496E3B1544EBB6B62FA (gene)

Gene Symbol:

WFIKKN1 Homo sapiens

Full name:

WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1

Synonyms:

C16orf12, RJD2, WFDC20A, WFIKKN, WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1, GASP-2, WAP four-disulfide core domain 20A, WAP, FS, Ig, KU, and NTR-containing protein, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing protein, growth and differentiation factor-associated serum protein 2, hGASP-2

Genomic Location:

Chr 16: 621013-624117

Description:

This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a multivalent protease inhi...

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This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a multivalent protease inhibitor and may control the action of multiple types of serine proteases as well as metalloproteinases.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MAZR_01 ,  VDR_Q6 ,  GGGAGGRR_MAZ_Q6 ,  GGGCGGR_SP1_Q6

Cytogenetic Map:

16p13.3

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