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QuickView for WFIKKN2;jsessionid=C11836744F93C496E3B1544EBB6B62FA (gene)


Gene Symbol:
WFIKKN2 Homo sapiens Homo sapiens
Full name:
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
Synonyms:
GASP-1, WFDC20B, WFIKKNRP, hGASP-1, WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2, WAP four-disulfide core domain 20B, WAP, FS, Ig, two KU and NTR module related protein, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein, WFIKKN-related protein, growth and differentiation factor-associated serum protein 1, multivalent protease inhibitor protein
Genomic Location:
Chr 17: 46267604-46274708
Description:
The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 17
17q21.33


Transcripts Names
NM_175575
NM_001330341
Protein Names
C9J6G4
Q6UXZ9
Q8TEU8



GO Molecular Function

transforming growth factor beta binding | endopeptidase inhibitor activity | cytokine binding | receptor antagonist activity | receptor inhibitor activity | enzyme inhibitor activity | signaling receptor binding | growth factor binding | molecular function regulator | protein binding | receptor regulator activity | serine-type endopeptidase inhibitor activity | metalloendopeptidase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity

GO Biological Process

negative regulation of signaling receptor activity | endopeptidase inhibitor activity | regulation of transforming growth factor beta receptor signaling pathway | negative regulation of cellular process | cell differentiation | striated muscle cell development | receptor antagonist activity | negative regulation of proteolysis | cellular process | negative regulation of signaling | regulation of proteolysis | response to growth factor | negative regulation of cellular metabolic process | regulation of binding | muscle structure development | muscle cell differentiation | regulation of cellular process | regulation of metabolic process | receptor inhibitor activity | response to transforming growth factor beta | response to stimulus | enzyme inhibitor activity | muscle cell development | roof of mouth development | regulation of DNA binding | negative regulation of metabolic process | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | muscle fiber development | molecular function regulator | negative regulation of cellular response to transforming growth factor beta stimulus | system development | regulation of signal transduction | multicellular organism development | negative regulation of catalytic activity | regulation of peptidase activity | regulation of catalytic activity | negative regulation of peptidase activity | extracellular negative regulation of signal transduction | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | negative regulation of cellular response to growth factor stimulus | negative regulation of DNA binding | negative regulation of binding | regulation of cellular protein metabolic process | cell communication | negative regulation of protein binding | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of protein metabolic process | striated muscle cell differentiation | regulation of cellular response to growth factor stimulus | cellular response to transforming growth factor beta stimulus | regulation of signaling receptor activity | receptor regulator activity | negative regulation of transforming growth factor beta receptor signaling pathway | response to organic substance | anatomical structure development | cell surface receptor signaling pathway | negative regulation of cellular protein metabolic process | serine-type endopeptidase inhibitor activity | transforming growth factor beta receptor signaling pathway | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of protein binding | cell development | metalloendopeptidase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity | regulation of endopeptidase activity | developmental process | negative regulation of hydrolase activity | skeletal system development | cellular response to organic substance | signal transduction | regulation of signaling | negative regulation of endopeptidase activity | cellular response to growth factor stimulus | multicellular organismal process

GO Cellular Component

extracellular region | extracellular space