QuickView for WNT receptor (gene)
- Gene Symbol:
- FZD5
Homo sapiens - Full name:
- frizzled class receptor 5
- Synonyms:
- C2orf31, HFZ5, frizzled-5, Wnt receptor, frizzled 5, seven transmembrane spanning receptor, frizzled family receptor 5, fz-5, fzE5, seven-transmembrane receptor frizzled-5
- Genomic Location:
- Chr 2: 208335555-208342388
- Description:
-
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
2q33.3
GO Molecular Function
kinase binding | peptide binding | amyloid-beta binding | protein kinase binding | transmembrane signaling receptor activity | enzyme binding | protein-containing complex binding | lipid binding | ubiquitin-like protein ligase binding | amide binding | signaling receptor activity | protein binding | ubiquitin protein ligase binding | Wnt-activated receptor activity | Wnt-protein binding
GO Biological Process
positive regulation of immune response | regulation of JUN kinase activity | regulation of T cell mediated immunity | regulation of interleukin-1 beta production | positive regulation of macromolecule biosynthetic process | regulation of intracellular protein transport | positive regulation of cellular component organization | developmental process involved in reproduction | regulation of cellular localization | regulation of localization | chorionic trophoblast cell differentiation | morphogenesis of an epithelium | eye development | regulation of autophagy | regulation of immune system process | negative regulation of cellular process | embryonic camera-type eye morphogenesis | regulation of MAP kinase activity | cell differentiation | nervous system development | neurogenesis | positive regulation of interleukin-1 beta secretion | positive regulation of phosphate metabolic process | regulation of organelle organization | generation of neurons | positive regulation of protein secretion | blood vessel morphogenesis | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | lymphocyte differentiation | cell maturation | positive regulation of immune effector process | reproductive system development | synapse assembly | canonical Wnt signaling pathway | beta-catenin destruction complex disassembly | positive regulation of adaptive immune response | immune system development | positive regulation of protein kinase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | tissue development | regulation of immune response | regulation of cellular process | leukocyte activation | labyrinthine layer morphogenesis | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | regulation of bicellular tight junction assembly | cellular response to molecule of bacterial origin | positive regulation of interferon-gamma production | positive regulation of cellular protein metabolic process | epithelium development | positive regulation of T cell cytokine production | regulation of establishment of planar polarity | cellular component organization | regulation of chorionic trophoblast cell proliferation | T cell activation | positive regulation of tumor necrosis factor production | regulation of peptide secretion | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | positive regulation of interleukin-1 beta production | vasculature development | regulation of cellular protein localization | positive regulation of protein targeting to mitochondrion | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of cellular protein localization | post-embryonic camera-type eye development | regulation of cell proliferation | tube morphogenesis | branching involved in labyrinthine layer morphogenesis | programmed cell death | reproduction | syncytiotrophoblast cell differentiation involved in labyrinthine layer development | positive regulation of cytokine secretion | cardiovascular system development | response to molecule of bacterial origin | blastoderm segmentation | regulation of protein transport | G-protein coupled receptor signaling pathway | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | hemopoiesis | cellular component assembly | regulation of peptide transport | Wnt signaling pathway, planar cell polarity pathway | embryo development | cell-cell signaling | regulation of intracellular transport | cell surface receptor signaling pathway involved in cell-cell signaling | positive regulation of mitochondrion organization | embryonic placenta development | blood vessel development | anterior/posterior pattern specification | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | leukocyte differentiation | regulation of cellular response to stress | apoptotic process | response to external biotic stimulus | system development | reproductive process | regulation of signal transduction | positive regulation of organelle organization | Wnt signaling pathway | post-embryonic animal organ development | multicellular organism development | positive regulation of tumor necrosis factor secretion | regulation of MAPK cascade | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of gene expression | positive regulation of secretion | embryonic axis specification | positive regulation of intracellular protein transport | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | regulation of nitrogen compound metabolic process | placenta blood vessel development | positive regulation of JNK cascade | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | synapse organization | regulation of T cell cytokine production | non-canonical Wnt signaling pathway | embryonic camera-type eye development | cell differentiation involved in embryonic placenta development | labyrinthine layer development | regulation of cellular protein metabolic process | angiogenesis | positive regulation of interleukin-1 secretion | labyrinthine layer blood vessel development | regulation of tumor necrosis factor production | post-embryonic development | sensory organ development | regulation of mitochondrion organization | response to bacterium | regulation of interleukin-1 production | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | eye morphogenesis | positive regulation of interleukin-1 production | anterior/posterior axis specification | regulation of cytokine production involved in immune response | regulation of protein metabolic process | positive regulation of signal transduction | apoptotic process involved in development | positive regulation of establishment of protein localization | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | positive regulation of transport | embryonic morphogenesis | regulation of autophagy of mitochondrion | lymphocyte activation | positive regulation of molecular function | regulation of cytokine secretion | neuron differentiation | embryonic organ morphogenesis | T cell differentiation | Wnt signaling pathway, calcium modulating pathway | regulation of establishment of protein localization | regionalization | axis specification | positive regulation of protein modification process | response to organic substance | T cell differentiation in thymus | tissue morphogenesis | regulation of kinase activity | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | Spemann organizer formation | anatomical structure development | cell surface receptor signaling pathway | regulation of interleukin-1 beta secretion | regulation of adaptive immune response | regulation of protein targeting | regulation of RNA biosynthetic process | developmental maturation | embryonic organ development | positive regulation of cytokine production involved in immune response | regulation of secretion | cell death | animal organ development | regulation of protein secretion | anterior/posterior axis specification, embryo | chorion development | positive regulation of kinase activity | regulation of tumor necrosis factor secretion | regulation of phosphate metabolic process | positive regulation of cytokine production | positive regulation of intracellular transport | regulation of JNK cascade | cell activation | positive regulation of MAPK cascade | positive regulation of T cell mediated immunity | morphogenesis of a branching epithelium | positive regulation of protein transport | camera-type eye development | anatomical structure formation involved in morphogenesis | regulation of stress-activated MAPK cascade | regulation of cell communication | Wnt-activated receptor activity | signaling | regulation of transcription, DNA-templated | cell development | protein-containing complex disassembly | positive regulation of phosphorylation | regulation of cytokine production | morphogenesis of a branching structure | anatomical structure morphogenesis | camera-type eye morphogenesis | positive regulation of MAP kinase activity | response to biotic stimulus | reproductive structure development | regulation of developmental process | segmentation | developmental process | tube development | regulation of cell junction assembly | regulation of transport | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | embryonic placenta morphogenesis | positive regulation of transcription by RNA polymerase II | positive regulation of JUN kinase activity | in utero embryonic development | positive regulation of metabolic process | apoptotic process involved in morphogenesis | regulation of interferon-gamma production | immune system process | hematopoietic or lymphoid organ development | embryonic eye morphogenesis | placenta development | regulation of protein localization | developmental induction | circulatory system development | regulation of cellular component organization | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | embryonic pattern specification | multicellular organismal process | regulation of protein targeting to mitochondrion | regulation of phosphorus metabolic process
GO Cellular Component
occluding junction | integral component of membrane | dendrite | intracellular membrane-bounded organelle | early endosome membrane | synapse | neuron projection | clathrin-coated endocytic vesicle membrane | endocytic vesicle membrane | clathrin-coated vesicle membrane | somatodendritic compartment | organelle membrane | clathrin-coated vesicle | cytoplasmic vesicle | cell body | cell | neuronal cell body | intrinsic component of membrane | cytoplasm | clathrin-coated endocytic vesicle | intracellular organelle | dendritic tree | cell-cell junction | endosome membrane | Golgi apparatus | cell projection | endomembrane system | plasma membrane | perikaryon | vesicle | perinuclear region of cytoplasm | integral component of plasma membrane | Golgi membrane | endosome | coated vesicle membrane | membrane-bounded organelle | apical junction complex | organelle | vesicle membrane | cell periphery | bicellular tight junction | axon | early endosome | intracellular vesicle | cell surface | endocytic vesicle | intracellular | cell junction | membrane | cytoplasmic vesicle membrane | intrinsic component of plasma membrane | coated vesicle
