QuickView for Wnt3a (gene)

GO Molecular Function

signaling receptor binding | molecular function regulator | protein domain specific binding | frizzled binding | co-receptor binding | transcription coactivator activity | protein binding | receptor regulator activity | G-protein coupled receptor binding | receptor ligand activity | transcription coregulator activity

GO Biological Process

brain development | positive regulation of striated muscle cell differentiation | positive regulation of mesodermal cell fate specification | cell morphogenesis | inner ear morphogenesis | positive regulation of macromolecule biosynthetic process | regulation of cysteine-type endopeptidase activity | extracellular structure organization | positive regulation of cellular component organization | regulation of B cell activation | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | regulation of cellular localization | muscle tissue development | positive regulation of skeletal muscle tissue development | positive regulation of apoptotic process | regulation of cell development | regulation of localization | morphogenesis of an epithelium | positive regulation of DNA-binding transcription factor activity | positive regulation of striated muscle tissue development | regulation of axon extension involved in axon guidance | positive regulation of embryonic development | regulation of programmed cell death | regulation of cardiac muscle cell differentiation | positive regulation of peptidyl-tyrosine phosphorylation | hippocampus development | establishment of localization | paraxial mesoderm morphogenesis | regulation of immune system process | negative regulation of neuron death | calcium ion transmembrane transport via low voltage-gated calcium channel | negative regulation of cellular process | neural tube patterning | positive regulation of developmental process | positive regulation of lymphocyte activation | regulation of protein localization to membrane | cell differentiation | positive regulation of epithelial cell proliferation | negative regulation of fat cell differentiation | nervous system development | cell part morphogenesis | positive regulation of axonogenesis | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | regulation of organelle organization | positive regulation of collateral sprouting | generation of neurons | mesenchyme development | pattern specification process | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | negative regulation of axonogenesis | localization | cell projection morphogenesis | epithelial tube morphogenesis | mesoderm morphogenesis | heart morphogenesis | metal ion transport | developmental growth | regulation of dopaminergic neuron differentiation | positive regulation of peptidyl-serine phosphorylation | neuron development | negative regulation of developmental growth | central nervous system neuron differentiation | determination of left/right symmetry | synapse assembly | canonical Wnt signaling pathway | beta-catenin destruction complex disassembly | negative regulation of heart induction by canonical Wnt signaling pathway | mesoderm development | regulation of embryonic development | immune system development | positive regulation of cell fate specification | regulation of striated muscle tissue development | positive regulation of protein kinase activity | macromolecule localization | hemostasis | regulation of chemotaxis | axon guidance | regulation of proteolysis | dorsal spinal cord development | regulation of hepatocyte proliferation | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation | regulation of neuron projection development | regulation of canonical Wnt signaling pathway | establishment of localization in cell | tissue development | regulation of binding | regulation of fat cell differentiation | regulation of cell differentiation | positive regulation of muscle cell differentiation | muscle structure development | regulation of cardioblast cell fate specification | muscle cell differentiation | skeletal muscle organ development | cellular response to retinoic acid | regulation of cellular process | positive regulation of cell growth | negative regulation of cardiocyte differentiation | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | spinal cord association neuron differentiation | negative regulation of chemotaxis | positive regulation of cellular protein metabolic process | epithelium development | regulation of axon guidance | cellular component organization | platelet aggregation | negative regulation of cell morphogenesis involved in differentiation | positive regulation of protein binding | head development | regulation of mesodermal cell fate specification | response to stimulus | cell morphogenesis involved in neuron differentiation | regulation of cellular protein localization | regulation of peptidyl-tyrosine phosphorylation | paraxial mesoderm development | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of peptidase activity | determination of heart left/right asymmetry | mesoderm formation | response to stress | neuron projection guidance | regulation of receptor internalization | positive regulation of cellular protein localization | positive regulation of lymphocyte proliferation | skeletal muscle tissue development | regulation of cell proliferation | negative regulation of neuron projection development | roof of mouth development | tube morphogenesis | cardiac muscle tissue development | positive regulation of cell-cell adhesion | positive regulation of cysteine-type endopeptidase activity | positive regulation of B cell proliferation | Wnt signaling pathway involved in forebrain neuroblast division | regulation of transcription regulatory region DNA binding | positive regulation of cell activation | cellular localization | divalent metal ion transport | positive regulation of proteolysis | midbrain development | axis elongation | extracellular matrix organization | regulation of DNA binding | regulation of cellular component size | positive regulation of RNA biosynthetic process | hemopoiesis | cellular component assembly | regulation of axon extension | regulation of cell adhesion | dorsal/ventral pattern formation | embryo development | cell-cell signaling | molecular function regulator | cell surface receptor signaling pathway involved in cell-cell signaling | positive regulation of collateral sprouting in absence of injury | anterior/posterior pattern specification | blood coagulation | regulation of nucleic acid-templated transcription | somatic stem cell division | locomotion | synaptic vesicle cycle | positive regulation of mononuclear cell proliferation | regulation of protein tyrosine kinase activity | regulation of skeletal muscle tissue development | system development | canonical Wnt signaling pathway involved in heart development | regulation of signal transduction | Wnt signaling pathway | negative regulation of growth | positive regulation of neuron projection development | multicellular organism development | regulation of peptidase activity | calcium ion transmembrane transport | neuroblast proliferation | mammary gland development | regulation of axonogenesis | positive regulation of muscle organ development | regulation of catalytic activity | regulation of phosphorylation | ion transmembrane transport | paraxial mesodermal cell fate commitment | wound healing | synaptic vesicle recycling | telencephalon development | regulation of receptor-mediated endocytosis | positive regulation of receptor-mediated endocytosis | positive regulation of protein localization to plasma membrane | determination of bilateral symmetry | regulation of neuron differentiation | regulation of gene expression | stem cell proliferation | regulation of cell fate specification | platelet activation | axon development | response to lipid | stem cell division | embryonic heart tube morphogenesis | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of lymphocyte activation | animal organ morphogenesis | regulation of cell-cell adhesion mediated by cadherin | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of cell projection organization | cardiocyte differentiation | regulation of cellular component movement | regulation of transcription by RNA polymerase II | synapse organization | axonogenesis | positive regulation of hydrolase activity | positive regulation of cell differentiation | axis elongation involved in somitogenesis | cell proliferation | cell division | neural tube development | neuronal stem cell division | regulation of cellular protein metabolic process | mesenchyme morphogenesis | positive regulation of endopeptidase activity | cellular protein-containing complex assembly | positive regulation of gastrulation | heart looping | cell morphogenesis involved in differentiation | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | sensory organ development | mesodermal cell fate commitment | chordate embryonic development | striated muscle tissue development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of core promoter binding | positive regulation of protein localization to membrane | positive regulation of dermatome development | regulation of protein metabolic process | dorsal/ventral neural tube patterning | positive regulation of signal transduction | inner ear development | heart development | limbic system development | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | embryo development ending in birth or egg hatching | transcription coactivator activity | regulation of RNA metabolic process | regulation of stem cell differentiation | positive regulation of B cell activation | positive regulation of transport | response to retinoic acid | striated muscle cell differentiation | negative regulation of cell growth | coagulation | negative regulation of cell fate commitment | embryonic morphogenesis | paraxial mesodermal cell differentiation | regulation of microtubule-based process | COP9 signalosome assembly | cell proliferation in forebrain | positive regulation of molecular function | negative regulation of cell fate specification | secondary palate development | neuron differentiation | cation transmembrane transport | embryonic organ morphogenesis | presynapse assembly | regulation of signaling receptor activity | receptor regulator activity | protein-containing complex assembly | regulation of cell morphogenesis involved in differentiation | regulation of mesoderm development | positive regulation of cell-cell adhesion mediated by cadherin | regionalization | positive regulation of protein modification process | regulation of growth | response to organic substance | gland development | regulation of cardiac muscle tissue development | negative regulation of cell projection organization | tissue morphogenesis | negative regulation of axon extension involved in axon guidance | regulation of kinase activity | response to wounding | regulation of animal organ morphogenesis | regulation of DNA-binding transcription factor activity | post-anal tail morphogenesis | regulation of cardiac cell fate specification | embryonic heart tube development | anatomical structure development | developmental growth involved in morphogenesis | cell surface receptor signaling pathway | positive regulation of neurogenesis | regulation of neural precursor cell proliferation | cell projection organization | positive regulation of cell development | cell fate commitment | regulation of collateral sprouting in absence of injury | regulation of protein localization to plasma membrane | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | regulation of body fluid levels | embryonic organ development | cellular protein localization | ear development | positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation | regulation of vesicle-mediated transport | negative regulation of axon extension | calcium ion transport | forebrain generation of neurons | positive regulation of cell death | cell adhesion | receptor ligand activity | midbrain dopaminergic neuron differentiation | neuron projection development | positive regulation of core promoter binding | animal organ development | forebrain development | negative regulation of neuron differentiation | pallium development | regulation of cell activation | negative regulation of cellular component movement | positive regulation of programmed cell death | positive regulation of kinase activity | regulation of heart morphogenesis | negative regulation of stem cell differentiation | regulation of Wnt signaling pathway | neural precursor cell proliferation | regulation of striated muscle cell differentiation | regulation of phosphate metabolic process | cell proliferation in midbrain | inorganic cation transmembrane transport | muscle cell fate commitment | negative regulation of dopaminergic neuron differentiation | positive regulation of binding | positive regulation of muscle tissue development | cell-cell adhesion | positive regulation of cytokine production | dopaminergic neuron differentiation | cell activation | positive regulation of canonical Wnt signaling pathway | regulation of peptidyl-serine phosphorylation | anatomical structure formation involved in morphogenesis | neuroblast division | cell differentiation in spinal cord | regulation of animal organ formation | positive regulation of cardiac muscle cell differentiation | cardiac muscle cell differentiation | regulation of collateral sprouting | regulation of cell communication | paraxial mesoderm formation | transmembrane transport | positive regulation of developmental growth | signaling | somite development | positive regulation of growth | regulation of transcription, DNA-templated | regulation of protein binding | cell development | positive regulation of DNA binding | regulation of endocytosis | regulation of developmental growth | protein localization | regulation of epithelial cell proliferation | protein-containing complex disassembly | positive regulation of phosphorylation | positive regulation of protein tyrosine kinase activity | regulation of cell size | regulation of cytokine production | anatomical structure morphogenesis | positive regulation of mesoderm development | regulation of endopeptidase activity | cation transport | cellular macromolecule localization | cell fate commitment involved in formation of primary germ layer | positive regulation of receptor internalization | regulation of nervous system development | regulation of developmental process | forebrain neuroblast division | positive regulation of neural precursor cell proliferation | segmentation | developmental process | regulation of muscle cell differentiation | regulation of cell growth | tube development | regulation of gastrulation | regulation of transport | positive regulation of transcription, DNA-templated | negative regulation of cardioblast cell fate specification | regulation of B cell proliferation | regulation of cell-cell adhesion | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | formation of primary germ layer | positive regulation of transcription by RNA polymerase II | positive regulation of cell fate commitment | positive regulation of hepatocyte proliferation | somitogenesis | regulation of cell fate commitment | central nervous system development | mesodermal cell differentiation | spinal cord development | in utero embryonic development | positive regulation of metabolic process | ossification | positive regulation of neuron differentiation | osteoblast differentiation | ion transport | regulation of type B pancreatic cell proliferation | regulation of cell projection organization | gastrulation | regulation of cardioblast differentiation | immune system process | positive regulation of Wnt signaling pathway | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of protein localization | regulation of cell death | positive regulation of cardiac muscle tissue development | positive regulation of cell morphogenesis involved in differentiation | negative regulation of cell death | negative regulation of cell development | circulatory system development | canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | chemotaxis | ear morphogenesis | negative regulation of locomotion | positive regulation of endocytosis | skeletal muscle cell differentiation | regulation of microtubule cytoskeleton organization | negative regulation of cell differentiation | regulation of cellular component organization | homotypic cell-cell adhesion | muscle organ development | regulation of cytoskeleton organization | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | positive regulation of transcription regulatory region DNA binding | regulation of muscle organ development | negative regulation of neurogenesis | multicellular organismal process | cardiac muscle cell fate commitment | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | early endosome membrane | synapse | endocytic vesicle membrane | organelle membrane | cytoplasmic vesicle | cell | plasma membrane protein complex | cytoplasm | intracellular organelle | endoplasmic reticulum | presynapse | endosome membrane | Golgi apparatus | protein-containing complex | endomembrane system | plasma membrane | vesicle | endoplasmic reticulum lumen | extracellular exosome | endosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | vesicle membrane | extracellular space | cell periphery | membrane-enclosed lumen | early endosome | intracellular vesicle | cell surface | endocytic vesicle | intracellular | membrane | cytoplasmic vesicle membrane | Wnt-Frizzled-LRP5/6 complex | Golgi lumen

PATHWAYS

PID_WNT_CANONICAL_PATHWAY | PID_BETA_CATENIN_DEG_PATHWAY | REACTOME_GPCR_LIGAND_BINDING | WNT_SIGNALING | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | REACTOME_SIGNALING_BY_GPCR | NABA_SECRETED_FACTORS | PID_WNT_SIGNALING_PATHWAY | NABA_MATRISOME | NABA_MATRISOME_ASSOCIATED

PROTEIN FAMILY

Wnt | Wnt-3 protein | Wnt protein, conserved site