QuickView for Wnt8b (gene)

Gene Symbol:

WNT8B Homo sapiens

Full name:

Wnt family member 8B

Synonyms:

protein Wnt-8b, wingless-type MMTV integration site family, member 8B

Genomic Location:

Chr 10: 102212802-102233389

Description:

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86%...

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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NKX25_01 ,  PR_Q2 ,  GATTGGY_NFY_Q6_01 ,  IRF1_01 ,  PAX4_04 ,  PR_02 ,  TGANTCA_AP1_C ,  GATA1_03 ,  ZIC1_01 ,  AP3_Q6 ,  AML_Q6 ,  PR_01 ,  SMAD3_Q6 ,  NFY_C ,  WGTTNNNNNAAA_UNKNOWN ,  CTTTGA_LEF1_Q2 ,  GR_Q6_01 ,  TTF1_Q6 ,  NKX22_01 ,  TTAYRTAA_E4BP4_01 ,  AML1_01 ,  WTGAAAT_UNKNOWN ,  LEF1_Q2 ,  TITF1_Q3 ,  MEF2_01 ,  NFY_Q6_01 ,  ALPHACP1_01 ,  CDX2_Q5 ,  HSF1_01 ,  LHX3_01 ,  TGCTGAY_UNKNOWN ,  CREBP1_01 ,  NFY_01 ,  OCT1_03 ,  S8_01 ,  NKX61_01 ,  NKX25_02 ,  NFY_Q6 ,  RACCACAR_AML_Q6 ,  AML1_Q6 ,  HAND1E47_01 ,  TAATTA_CHX10_01 ,  GR_01 ,  PIT1_Q6 ,  IK2_01 ,  WTTGKCTG_UNKNOWN ,  YTAATTAA_LHX3_01 ,  CAGCTG_AP4_Q5 ,  ISRE_01 ,  AACTTT_UNKNOWN ,  ER_Q6 ,  RYTAAWNNNTGAY_UNKNOWN

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Cytogenetic Map:

10q24.31

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