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QuickView for XM_011534097 (gene)


Gene Symbol:
CACNA1D Homo sapiens Homo sapiens
Full name:
calcium voltage-gated channel subunit alpha1 D
Synonyms:
CACH3, CACN4, CACNL1A2, CCHL1A2, Cav1.3, PASNA, SANDD, voltage-dependent L-type calcium channel subunit alpha-1D, calcium channel, L type, alpha-1 polypeptide, calcium channel, neuroendocrine/brain-type, alpha 1 subunit, calcium channel, voltage-dependent, L type, alpha 1D subunit, voltage-gated calcium channel alpha 1 subunit, voltage-gated calcium channel alpha subunit Cav1.3
Genomic Location:
Chr 3: 53504116-53821001
Description:
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Danio rerio Bos taurus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 3
3p21.1





GO Molecular Function

high voltage-gated calcium channel activity | voltage-gated ion channel activity | cation binding | passive transmembrane transporter activity | transmembrane transporter activity | ion gated channel activity | alpha-actinin binding | voltage-gated calcium channel activity | cytoskeletal protein binding | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | ion binding | ankyrin binding | protein binding | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cation channel activity | voltage-gated calcium channel activity involved SA node cell action potential | inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | calcium channel activity | voltage-gated calcium channel activity involved in cardiac muscle cell action potential | actinin binding | metal ion binding | ion channel activity | substrate-specific channel activity

GO Biological Process

heart process | actin filament-based process | regulation of localization | high voltage-gated calcium channel activity | establishment of localization | membrane depolarization during action potential | voltage-gated ion channel activity | regulation of peptide hormone secretion | sensory perception of mechanical stimulus | calcium ion import | cellular process | localization | passive transmembrane transporter activity | metal ion transport | actin filament-based movement | regulation of cellular process | membrane depolarization during cardiac muscle cell action potential | transmembrane transporter activity | heart contraction | actin-mediated cell contraction | regulation of peptide secretion | regulation of atrial cardiac muscle cell membrane repolarization | muscle contraction | response to stimulus | ion gated channel activity | regulation of insulin secretion | regulation of blood circulation | regulation of heart rate | divalent metal ion transport | regulation of protein transport | blood circulation | G-protein coupled receptor signaling pathway | regulation of peptide transport | cell-cell signaling | regulation of potassium ion transmembrane transport | regulation of membrane potential | voltage-gated calcium channel activity | calcium ion transmembrane transport | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | regulation of hormone levels | ion transmembrane transport | regulation of hormone secretion | SA node cell to atrial cardiac muscle cell communication | nervous system process | cation transmembrane transporter activity | cardiac muscle cell action potential involved in contraction | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | SA node cell action potential | cell-cell signaling involved in cardiac conduction | regulation of heart contraction | regulation of potassium ion transmembrane transporter activity | cell communication | membrane depolarization during SA node cell action potential | cardiac muscle cell contraction | sensory perception of sound | positive regulation of transport | striated muscle contraction | regulation of potassium ion transport | cation transmembrane transport | regulation of establishment of protein localization | regulation of heart rate by cardiac conduction | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cell communication involved in cardiac conduction | calcium ion transport | regulation of secretion | membrane depolarization | positive regulation of ion transport | regulation of protein secretion | SA node cell to atrial cardiac muscle cell signaling | inorganic cation transmembrane transport | regulation of ion transmembrane transport | cation channel activity | sensory perception | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | voltage-gated calcium channel activity involved SA node cell action potential | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | voltage-gated channel activity | cation transport | channel activity | regulation of ion transport | calcium channel activity | regulation of calcium ion transport | voltage-gated calcium channel activity involved in cardiac muscle cell action potential | regulation of transport | cardiac muscle cell action potential | ion channel activity | ion transport | cardiac muscle contraction | regulation of protein localization | substrate-specific channel activity | regulation of membrane repolarization | positive regulation of calcium ion transport | muscle system process | signal transduction | regulation of signaling | cardiac conduction | multicellular organismal process

GO Cellular Component

supramolecular fiber | integral component of membrane | sarcolemma | sarcomere | voltage-gated calcium channel complex | cell | plasma membrane protein complex | intrinsic component of membrane | myofibril | cytoplasm | intracellular organelle | contractile fiber | protein-containing complex | plasma membrane | T-tubule | calcium channel complex | organelle | I band | cell periphery | L-type voltage-gated calcium channel complex | transmembrane transporter complex | cation channel complex | ion channel complex | Z disc | intracellular | membrane | supramolecular complex