QuickView for YFH1 (gene)
- Gene Symbol:
- YFH1
Saccharomyces cerevisiae - Full name:
- Frataxin, regulates mitochondrial iron accumulation; interacts with Isu1p which promotes Fe-S cluster assembly; interacts with electron transport chain components and may influence respiration; human homolog involved in Friedrich's ataxia
- Synonyms:
- YDL120W, YFH1
- Genomic Location:
- Chr IV: 245923-246447
- Orthologs:
- D. melanogaster , C. elegans
- External Links:
- Entrez Gene
GO Molecular Function
cofactor binding | ferric iron binding | cation binding | ferrous iron binding | iron chaperone activity | iron ion binding | oxidoreductase activity, oxidizing metal ions | catalytic activity | iron-sulfur cluster binding | ferroxidase activity | ion binding | 2 iron, 2 sulfur cluster binding | metallochaperone activity | transition metal ion binding | metal ion binding | oxidoreductase activity
GO Biological Process
sulfur compound metabolic process | glutathione metabolic process | establishment of localization | cellular chemical homeostasis | cellular process | localization | cellular homeostasis | heme metabolic process | porphyrin-containing compound metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | iron-sulfur cluster assembly | oxidoreductase activity, oxidizing metal ions | cellular nitrogen compound biosynthetic process | tetrapyrrole biosynthetic process | cellular nitrogen compound metabolic process | cofactor metabolic process | cellular component assembly | protein modification process | cellular biosynthetic process | mitochondrion organization | macromolecule modification | metal ion homeostasis | nitrogen compound metabolic process | cellular ion homeostasis | cofactor biosynthetic process | pigment biosynthetic process | cellular amide metabolic process | heme biosynthetic process | biosynthetic process | aromatic compound biosynthetic process | ferroxidase activity | cation homeostasis | cellular cation homeostasis | homeostatic process | peptide metabolic process | iron ion homeostasis | protein metabolic process | metabolic process | oxidation-reduction process | chemical homeostasis | organic substance metabolic process | pigment metabolic process | ion homeostasis | cellular iron ion homeostasis | iron incorporation into metallo-sulfur cluster | cellular protein metabolic process | organelle organization | cellular protein modification process | cellular metal ion homeostasis | cellular modified amino acid metabolic process | heterocycle metabolic process | ion transport | transition metal ion homeostasis | cellular metabolic process | oxidoreductase activity | porphyrin-containing compound biosynthetic process | macromolecule metabolic process
GO Cellular Component
mitochondrial matrix | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | membrane-enclosed lumen | intracellular
