QuickView for ZFP36L1;jsessionid=FA902B44B6859B06376DB8A60F248A89 (gene)

Gene Symbol:

ZFP36L1 Homo sapiens

Full name:

ZFP36 ring finger protein like 1

Synonyms:

BRF1, Berg36, ERF-1, ERF1, RNF162B, TIS11B, cMG1, mRNA decay activator protein ZFP36L1, EGF-response factor 1, TPA-induced sequence 11b, ZFP36-like 1, butyrate response factor 1, early response factor Berg36, zinc finger protein 36, C3H type-like 1, zinc finger protein 36, C3H1 type-like 1, zinc finger protein, C3H type, 36-like 1

Genomic Location:

Chr 14: 68324128-68329538

Description:

This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc fin...

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This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Saccharomyces cerevisiae ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  CACTGTG_MIR128A_MIR128B ,  PBX1_02 ,  OCT1_05 ,  SMTTTTGT_UNKNOWN ,  TGANTCA_AP1_C ,  TTTGCAG_MIR518A2 ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  EFC_Q6 ,  SREBP1_02 ,  HOXA4_Q2 ,  TTGCWCAAY_CEBPB_02 ,  TGTGTGA_MIR377 ,  CEBP_Q2_01 ,  HP1SITEFACTOR_Q6 ,  AMEF2_Q6 ,  GATAAGR_GATA_C ,  TAGCTTT_MIR9 ,  HNF1_C ,  SREBP1_Q6 ,  CTTTGA_LEF1_Q2 ,  AP2ALPHA_01 ,  ATCTTGC_MIR31 ,  MYCMAX_B ,  ACTGTGA_MIR27A_MIR27B ,  WTGAAAT_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  YAATNRNNNYNATT_UNKNOWN ,  TGAYRTCA_ATF3_Q6 ,  TATAAA_TATA_01 ,  CEBP_Q2 ,  GCTTGAA_MIR498 ,  TTGGAGA_MIR5155P_MIR519E ,  ACATTCC_MIR1_MIR206 ,  GCACCTT_MIR18A_MIR18B ,  GGATTA_PITX2_Q2 ,  CAGGTG_E12_Q6 ,  EGR_Q6 ,  CTCAAGA_MIR526B ,  ATTCTTT_MIR186 ,  GCAAAAA_MIR129 ,  ATF3_Q6 ,  GGGCGGR_SP1_Q6 ,  ATGTTAA_MIR302C ,  GTGCCAA_MIR96 ,  OCT1_03 ,  NKX61_01 ,  RAAGNYNNCTTY_UNKNOWN ,  CTTTAAR_UNKNOWN ,  PTF1BETA_Q6 ,  RORA1_01 ,  STAT_01 ,  GTGCCTT_MIR506 ,  TTGCCAA_MIR182 ,  CHX10_01 ,  HAND1E47_01 ,  TAATTA_CHX10_01 ,  YTAAYNGCT_UNKNOWN ,  MYOGENIN_Q6 ,  IRF7_01 ,  SREBP_Q3 ,  ZIC2_01 ,  CTGCAGY_UNKNOWN ,  GTGGGTGK_UNKNOWN ,  TAL1BETAITF2_01 ,  RORA2_01 ,  CTCTAGA_MIR526C_MIR518F_MIR526A ,  CTTTGT_LEF1_Q2 ,  TBP_01 ,  ER_Q6_02 ,  CAGCTG_AP4_Q5 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  AACTTT_UNKNOWN ,  ER_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-10 ,  Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-129 ,  Predicted Gene Targets for miR-138 ,  Predicted Gene Targets for miR-139 ,  Predicted Gene Targets for miR-143 ,  Predicted Gene Targets for miR-18 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-377 ,  Predicted Gene Targets for miR-431 ,  Predicted Gene Targets for miR-450 ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-299-3p ,  Predicted Gene Targets for miR-29 ,  Predicted Gene Targets for miR-31 ,  Predicted Gene Targets for miR-495

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Cytogenetic Map:

14q24.1

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