QuickView for ZFP57 (gene)
- Gene Symbol:
- ZFP57
Homo sapiens - Full name:
- ZFP57 zinc finger protein
- Synonyms:
- C6orf40, TNDM1, ZNF698, bA145L22, bA145L22.2, zinc finger protein 57 homolog, zfp-57, zinc finger protein 698
- Genomic Location:
- Chr 6: 29748239-29756866
- Description:
-
The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor. Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1).
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
6p22.1
GO Molecular Function
RNA polymerase II transcription factor activity, sequence-specific DNA binding | cation binding | nucleic acid binding | DNA binding | ion binding | organic cyclic compound binding | DNA-binding transcription factor activity | metal ion binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | DNA modification | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cellular process | regulation of gene expression, epigenetic | DNA methylation involved in embryo development | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | genetic imprinting | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | embryo development | macromolecule modification | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | multicellular organism development | regulation of gene expression | methylation | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | DNA methylation | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | regulation of gene expression by genetic imprinting | DNA-binding transcription factor activity | DNA metabolic process | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | developmental process | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
