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QuickView for ZNF274 (gene)


Gene Symbol:
ZNF274 Homo sapiens Homo sapiens
Full name:
zinc finger protein 274
Synonyms:
HFB101, ZF2, ZKSCAN19, ZSCAN51, neurotrophin receptor-interacting factor homolog, KRAB zinc finger protein HFB101, zinc finger protein HFB101, zinc finger protein with KRAB and SCAN domains 19, zinc finger protein zfp2
Genomic Location:
Chr 19: 63386208-63416739
Description:
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different is...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 19
19q13.43





GO Molecular Function

sequence-specific DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cation binding | nucleic acid binding | chromatin binding | DNA binding | transcription corepressor activity | ion binding | organic cyclic compound binding | protein binding | DNA-binding transcription factor activity | transcription coregulator activity | metal ion binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | regulation of organelle organization | cellular process | regulation of histone H3-K9 trimethylation | regulation of histone H3-K9 methylation | negative regulation of nucleic acid-templated transcription | regulation of histone modification | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | regulation of histone methylation | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | regulation of nitrogen compound metabolic process | transcription corepressor activity | regulation of transcription by RNA polymerase II | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of RNA metabolic process | DNA-binding transcription factor activity | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | gene expression | regulation of chromosome organization | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | transcription coregulator activity | heterocycle metabolic process | cellular metabolic process | regulation of cellular component organization | macromolecule metabolic process | regulation of chromatin organization

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular