QuickView for ZNF598 (gene)
- Gene Symbol:
- ZNF598
Homo sapiens - Full name:
- zinc finger protein 598
- Synonyms:
- HEL2, E3 ubiquitin-protein ligase ZNF598
- Genomic Location:
- Chr 16: 1987769-1999764
- Description:
-
Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This protein and Grb10-interacting GYF protein 2 have been identified as a components of the mammalian 4EHP (m4EHP) complex. The complex is thought to function as a translation repressor in em...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
16p13.3
GO Molecular Function
cation binding | nucleic acid binding | protein-containing complex binding | catalytic activity | ribonucleoprotein complex binding | ubiquitin-like protein transferase activity | ubiquitin protein ligase activity | ion binding | organic cyclic compound binding | ribosome binding | protein binding | ubiquitin-protein transferase activity | transferase activity | ubiquitin-like protein ligase activity | metal ion binding | heterocyclic compound binding | RNA binding
GO Biological Process
rescue of stalled ribosome | translational elongation | cellular process | regulation of cellular process | regulation of metabolic process | peptide biosynthetic process | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | cellular nitrogen compound metabolic process | protein modification process | cellular biosynthetic process | macromolecule modification | nitrogen compound metabolic process | protein monoubiquitination | regulation of gene expression | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | cellular amide metabolic process | ubiquitin protein ligase activity | translation | biosynthetic process | regulation of cellular protein metabolic process | regulation of cellular metabolic process | regulation of protein metabolic process | peptide metabolic process | protein metabolic process | protein ubiquitination | metabolic process | ubiquitin-protein transferase activity | organic substance metabolic process | gene expression | amide biosynthetic process | protein modification by small protein conjugation or removal | cellular protein metabolic process | cellular macromolecule biosynthetic process | cellular protein modification process | cellular metabolic process | regulation of translation | macromolecule metabolic process
GO Cellular Component
