QuickView for ZNRF1;jsessionid=E67AC4A221E7BD3706243AB3FA8CCE97 (gene)

Gene Symbol:

ZNRF1 Homo sapiens

Full name:

zinc and ring finger 1

Synonyms:

NIN283, E3 ubiquitin-protein ligase ZNRF1, RING-type E3 ubiquitin transferase ZNRF1, nerve injury gene 283, nerve injury-induced gene 283 protein, zinc and ring finger 1, E3 ubiquitin protein ligase, zinc and ring finger protein 1, zinc/RING finger protein 1

Genomic Location:

Chr 16: 73590416-73702393

Description:

This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein...

View Full Description

This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GAGCCTG_MIR484 ,  ZF5_01 ,  YATTNATC_UNKNOWN ,  VDR_Q6 ,  LYF1_01 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  STAT1_03 ,  GGGCATT_MIR365 ,  E2F1_Q4 ,  GGGAGGRR_MAZ_Q6 ,  CAGGTA_AREB6_01 ,  GGATTA_PITX2_Q2 ,  CAGGTG_E12_Q6 ,  TGCACTG_MIR148A_MIR152_MIR148B ,  AREB6_01 ,  TTGCCAA_MIR182 ,  ARGGGTTAA_UNKNOWN ,  IK1_01 ,  CTGCAGY_UNKNOWN ,  GGCCAGT_MIR193A_MIR193B ,  TCCATTKW_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  NFKB_Q6_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-129 ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-193 ,  Predicted Gene Targets for miR-204 ,  Predicted Gene Targets for miR-219 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-365 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-410

Cytogenetic Map:

16q23.1

search → result