QuickView for ZPA (gene)

Gene Symbol:

ZP2 Homo sapiens

Full name:

zona pellucida glycoprotein 2

Synonyms:

ZPA, Zp-2, zona pellucida sperm-binding protein 2, zona pellucida glycoprotein 2 (sperm receptor), zona pellucida glycoprotein ZP2, zona pellucida protein A

Genomic Location:

Chr 16: 21116274-21130369

Description:

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed of three glycoproteins with various functions during fertilization and preimplantation development. The glycosylated mature peptide is one of the structural components of the zona pellucida and functions in secondary binding and penetration of a...

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The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed of three glycoproteins with various functions during fertilization and preimplantation development. The glycosylated mature peptide is one of the structural components of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. Female mice lacking this gene do not form a stable zona matrix and are sterile. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Gallus gallus ,  Pan troglodytes

External Links:

Entrez Gene

Cytogenetic Map:

16p12.3-p12.2

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